STING Induces Liver Ischemia-Reperfusion Injury by Promoting Calcium-Dependent Caspase 1-GSDMD Processing in Macrophages

<div>The expression of STING in liver macrophages was induced by hypoxia-reoxygenation (H/R) treatment. KCs were isolated from the liver and treated with H/R. (a) STING expression in the control group and the H/R group was measured by Western blotting. (b) Relative expression of STING in each group. (c) The mRNA levels of STING were measured by quantitative real-time PCR. (d) The colocalization of F4/80 and STING in KCs was measured by confocal laser scanning microscopy (CLSM) in each group (scale bar, 20 <i>μ</i>m). 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Oxidative Medicine and Cellular Longevity

fig2

Figure 2

Figure 2: STING Induces Liver Ischemia-Reperfusion Injury by Promoting Calcium-Dependent Caspase 1-GSDMD Processing in Macrophages 