Osthole Induces Apoptosis and Caspase-3/GSDME-Dependent Pyroptosis via NQO1-Mediated ROS Generation in HeLa Cells

Figure 4

Label-free quantitative proteomic analysis. (a) Venn diagram shows the coincident proteins and special protein between treated and untreated groups. (b) Volcano plot shows the difference in expression between treated and untreated cells. Red dots represent the upregulated proteins, and blue dots represent downregulated protein while grey dots represent unchanged proteins (, ). (c) Heat map of differentially expressed proteins (, ). (d) KEGG pathway analysis of differentially expressed proteins. (e) Mitochondria-related differentially expressed proteins. All data are represented as ; ; , , and compared with the control group.

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