Melatonin Alleviates PM_2.5-Induced Hepatic Steatosis and Metabolic-Associated Fatty Liver Disease in ApoE^-/- Mice

Figure 5

PM_2.5 induced lipid accumulation in hepatocytes by increasing ROS levels and PTP1B expression. (a) BODIPY staining of L02 cells (scale bar, 50 μm). (b) Representative fluorescence intensity images obtained from flow cytometry in L02 cells. (c) Analysis of fluorescence intensity obtained from flow cytometry. (d) Representative confocal images of ROS. (e) Western blotting of PTP1B, PP2A, P-PP2A, SP1, P-SP1, and SREBP-1. (f) Protein quantification of PTP1B. (g) Protein quantification of P-PP2A/PP2A. (h) Protein quantification of P-SP1/SP1. (i) Protein quantification of SREBP-1. All values are presented as the . .

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