[Retracted] Aquaporin 4 Depolarization-Enhanced Transferrin Infiltration Leads to Neuronal Ferroptosis after Subarachnoid Hemorrhage in Mice

Figure 2

AQP4 overexpression improves SAH-induced AQP4 depolarization. (a, g) Immunofluorescence staining analysis of perivascular AQP4 expression changes in mouse temporal cortex large vessels 24 h after SAH. per group. CD31: red, AQP4: green; DAPI: blue.  μm. Data are the . (b, c, h, i) Representative immunofluorescence images of blood vessels in the cortex of (b) sham, (c) SAH, (h) SAH+vector, and (i) SAH+AAV-AQP4 group mice stained for AQP4 and CD31, illustrating placement of the 40 μm axis perpendicular to blood vessels for quantification of expression across vessel cross-sections, illustrating AQP4 expression surrounding blood vessels in the cortex. Ten cross-sections of one blood vessel from one mouse were selected. (d) Viral vector pattern diagram. (e) Immunofluorescence intensity statistics for AQP4. Data are the (ANOVA ; , post hoc Tukey’s test). (f) Quantification of AQP4 polarization. per group (ANOVA ; ; post hoc Tukey’s test).

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