Mitochondrial DNA and Epigenetics: Investigating Interactions with the One-Carbon Metabolism in Obesity

Table 1

Blood levels of 1C metabolism intermediates, related to nutrition, in the two groups (control vs. obese). The -test was used to identify significant differences between the groups. Hcy: homocysteine; GSH: glutathione.

	Controls ()				Overweight/obese ()
	Min	Max	Mean	SD	Min	Max	Mean	SD
Hcy (μM)	5.58	29.95	10.64	3.55	5.07	21.95	10.71	3.15	>0.05
GSH (μM)	2.60	24.26	11.52	3.94	2.18	17.74	8.97	3.68
Folate (ng/mL)	9.72	98.76	37.12	12.99	1.23	77.32	34.85	11.87	>0.05
Betaine (μM)	8.92	110.29	38.09	14.62	7.77	75.93	35.07	12.85	>0.05
Choline (μM)	3.54	10.76	6.10	1.35	3.20	11.01	6.32	1.47	>0.05
Vitamin B12 (μM)	0.32	16.49	2.34	1.96	0.46	13.10	2.08	1.82	0.045