Research Article

Preparation and Multitarget Anti-AD Activity Study of Chondroitin Sulfate Lithium in AD Mice Induced by Combination of D-Gal/AlCl3

Figure 1

Characterization of CS and CS-Li. (a) 1H NMR spectra of CS and CS-Li and (b) FTIR spectra of CS and CS-Li. (c) Cytotoxicity of CS-Li in SH-SY5Y cells: 1: control; 2: CS-Li 100 μg/mL and LiCl (amount of Li was equal to 100 μg/mL of CS-Li); 3: CS-Li 200 μg/mL and LiCl (amount of Li was equal to 200 μg/mL of CS-Li); 4: CS-Li 400 μg/mL and LiCl (amount of Li was equal to 400 μg/mL of CS-Li); 5: CS-Li 800 μg/mL and LiCl (amount of Li was equal to 800 μg/mL of CS-Li); vs. the CS-Li group.
(a)
(b)
(c)