Assessing the Potential Value and Mechanism of Kaji-Ichigoside F1 on Arsenite-Induced Skin Cell Senescence

<div>Arsenic can induce the skin cell senescence by promoting the level of SASP secretion and cell cycle arrest in cells. The in vitro results were based on 6 independent experiments. 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(a) The concentration of inflammatory factors. (b) The concentration of matrix remodeling factors and growth factors. (c) The cell cycle for each group. (d) The cell cycle analysis of flow cytometry. (e) The relative mRNA expression of p21 and p16INK4a to cell cycle regulation. (f) The relative protein expression of p21 and p16INK4a to cell cycle regulation. (g) The western blot for p21 and p16INK4a.</div>

Oxidative Medicine and Cellular Longevity

fig1

Figure 1

Figure 1: Assessing the Potential Value and Mechanism of Kaji-Ichigoside F1 on Arsenite-Induced Skin Cell Senescence