SEMA6D, Negatively Regulated by miR-7, Contributes to C28/I2 chondrocyte’s Catabolic and Anabolic Activities via p38 Signaling Pathway

<div>SEMA6D regulated the expression level of COL2A1 via p38 signaling pathway determined by immunofluorescence staining. Down-regulation of SEMA6D led to the lower fluorescence intensity that is the reduced expression of COL2A1, while up-regulation of SEMA6D displayed the opposite effect.</div>

Oxidative Medicine and Cellular Longevity

fig9

Figure 9

Figure 9: SEMA6D, Negatively Regulated by miR-7, Contributes to C28/I2 chondrocyte’s Catabolic and Anabolic Activities via p38 Signaling Pathway 