Oxidative Medicine and Cellular Longevity

Dietary Polyphenols and Their Effects on Cell Biochemistry and Pathophysiology 2013


Publishing date
22 Nov 2013
Status
Published
Submission deadline
05 Jul 2013

Lead Editor

1Department of Surgical, Medical, Dental and Morphological Sciences, University of Modena and Reggio Emilia, Modena, Italy

2Department of Nutrition, Norwich Medical School, University of East Anglia, Norwich, UK

3Department of Life Quality Studies, Alma Mater Studiorum, University of Bologna, Bologna, Italy


Dietary Polyphenols and Their Effects on Cell Biochemistry and Pathophysiology 2013

Description

Dietary polyphenols, along with other natural compounds occurring in fruit and vegetables, beverages such as wine and tea, extra virgin olive oil, chocolate, and other cocoa-derived products, have been reported to exert beneficial effects in a multitude of disease states, including cancer, cardiovascular disease, and neurodegenerative disorders. Historically, many of the biological actions of polyphenols have been attributed to their antioxidant properties, either through their reducing capacities per se or through their possible influences on intracellular redox status. However, during the last years, a new realisation of how nutritional antioxidants may function has been envisaged, and recent findings have suggested that, in complex biological systems and in lower amounts, typical of those attained in the diet, such molecules may exert several additional properties which are yet poorly understood.

As antioxidants, these natural compounds may protect cell constituents against oxidative damage, therefore limiting the risk of various oxidative stress-related degenerative diseases, such as cardiovascular diseases, type 2 diabetes, and cancer. However, accumulating evidence indicates that the classical hydrogen-donating antioxidant activity is unlikely to be the sole explanation for cellular effects of polyphenols and other natural compounds. It is evident that such dietary nutrients are potent bioactive molecules, and a clear understanding of their precise mechanisms of action as either antioxidants or modulators of cell signaling is crucial to the evaluation of their potential as anticancer agents and inhibitors of neurodegeneration.

We invite investigators to contribute original research articles as well as review articles that will stimulate the continuing efforts to understand the precise effects of polyphenols and other natural compounds in vitro and in vivo. We are particularly interested in articles describing the molecular mechanisms of action by which these molecules exert their beneficial or toxic effects in degenerative diseases. Potential topics include, but are not limited to:

  • Role of polyphenols and other natural compounds in molecular signalling
  • Role of polyphenols and other natural compounds in redox modulation
  • Effect of polyphenols and other natural compounds on apoptosis induction
  • Potential effect of polyphenols and other natural compounds in cancer
  • Potential effect of polyphenols and other natural compounds in neurodegenerative diseases
  • Potential effect of polyphenols and other natural compounds in cardiovascular diseases
  • Potential effect of polyphenols and other natural compounds in stem cell proliferation and differentiation

Before submission authors should carefully read over the journal’s Author Guidelines, which are located at http://www.hindawi.com/journals/oximed/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/oximed/dpecb13/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2014
  • - Article ID 576363
  • - Editorial

Dietary Polyphenols and Their Effects on Cell Biochemistry and Pathophysiology 2013

Tullia Maraldi | David Vauzour | Cristina Angeloni
  • Special Issue
  • - Volume 2014
  • - Article ID 706269
  • - Research Article

On the Molecular Pharmacology of Resveratrol on Oxidative Burst Inhibition in Professional Phagocytes

Radomír Nosáľ | Katarína Drábiková | ... | Juraj Harmatha
  • Special Issue
  • - Volume 2013
  • - Article ID 680816
  • - Research Article

Inhibition of Nuclear Nox4 Activity by Plumbagin: Effect on Proliferative Capacity in Human Amniotic Stem Cells

Marianna Guida | Tullia Maraldi | ... | Anto De Pol
  • Special Issue
  • - Volume 2013
  • - Article ID 695936
  • - Research Article

Moringa oleifera Mitigates Memory Impairment and Neurodegeneration in Animal Model of Age-Related Dementia

Chatchada Sutalangka | Jintanaporn Wattanathorn | ... | Wipawee Thukham-mee
  • Special Issue
  • - Volume 2013
  • - Article ID 951415
  • - Research Article

Cerebroprotective Effect of Moringa oleifera against Focal Ischemic Stroke Induced by Middle Cerebral Artery Occlusion

Woranan Kirisattayakul | Jintanaporn Wattanathorn | ... | Jinatta Jittiwat
  • Special Issue
  • - Volume 2013
  • - Article ID 486419
  • - Research Article

Antigenotoxic and Apoptotic Activity of Green Tea Polyphenol Extracts on Hexavalent Chromium-Induced DNA Damage in Peripheral Blood of CD-1 Mice: Analysis with Differential Acridine Orange/Ethidium Bromide Staining

María del Carmen García-Rodríguez | Megumi Monserrat Carvente-Juárez | Mario Agustín Altamirano-Lozano
  • Special Issue
  • - Volume 2013
  • - Article ID 596496
  • - Research Article

Quercetin Induces Mitochondrial Mediated Apoptosis and Protective Autophagy in Human Glioblastoma U373MG Cells

Hyeonji Kim | Jeong Yong Moon | ... | Somi Kim Cho
  • Special Issue
  • - Volume 2013
  • - Article ID 568093
  • - Review Article

Renal Protective Effects of Resveratrol

Munehiro Kitada | Daisuke Koya
  • Special Issue
  • - Volume 2013
  • - Article ID 271602
  • - Review Article

Natural Compounds as Modulators of NADPH Oxidases

Tullia Maraldi
  • Special Issue
  • - Volume 2013
  • - Article ID 456253
  • - Research Article

Rosmarinic Acid-Rich Extracts of Summer Savory (Satureja hortensis L.) Protect Jurkat T Cells against Oxidative Stress

Irakli Chkhikvishvili | Tamar Sanikidze | ... | Victor Rodov
Oxidative Medicine and Cellular Longevity
 Journal metrics
Acceptance rate44%
Submission to final decision79 days
Acceptance to publication45 days
CiteScore4.520
Impact Factor4.868
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