Oxidative Medicine and Cellular Longevity

Dietary Supplements/Antioxidants: Impact on Redox Status in Brain Diseases


Publishing date
16 Dec 2016
Status
Published
Submission deadline
29 Jul 2016

1Sultan Qaboos University, Muscat, Oman

2National Institutes of Health, Bethesda, USA

3Macquarie University, Sydney, Australia

4Annamalai University, Chidambaram, Tamil Nadu, India


Dietary Supplements/Antioxidants: Impact on Redox Status in Brain Diseases

Description

Oxidative stress plays a major role in neurodegenerative diseases and many other chronic diseases. Healthy diets rich in natural products could decrease the risk and outcome of brain diseases. Nature has gifted mankind with a plethora of flora-bearing fruits, vegetables, and nuts. Accumulated evidence suggests that naturally occurring phytocompounds, such as polyphenolic antioxidants found in fruits, vegetables, herbs, and nuts, may potentially hinder neurodegeneration and improve memory and cognitive function. Considering the limits of effective preventive agents and/or methods, intervention strategies using antioxidant and flavonoid-rich natural products such as fruits, vegetables, and nuts are of paramount importance. Usage of neuroprotective antioxidants is being considered as a promising approach to delay the progression of various chronic diseases and has the ability to reduce the functional neuronal loss in acute and chronic neurodegeneration of the brain. Diets rich in phytochemicals such as alkaloids, terpenes, flavonoids, isoflavones, and saponins are known to possess protective activity against many neurological diseases. The molecular mechanisms underlying the curative effects rely mainly on the action of phytonutrients on distinct signaling pathways associated with protein folding, oxidative modifications, and neuroinflammation. The diverse array of bioactive nutrients present in these natural products plays a pivotal role in prevention and cure of various neurodegenerative diseases including Alzheimer’s disease, Parkinson’s disease, and other neuronal dysfunctions.

This special issue aims to update the benefit of healthy diet rich in natural products and its importance in controlling the status of oxidative stress, inflammation, cognition, memory, behavior, and other biochemical abnormalities in neurodegenerative diseases and other brain disease conditions.

We invite investigators to contribute original research as well as review articles that will stimulate continuing efforts to improve or delay the progression of various brain diseases and finding novel leads for the development of possible therapeutics.

Potential topics include, but are not limited to:

  • Recent advancements in the involvement of oxidative stress in neurodegeneration
  • Effect of natural products and antioxidants on neurodegenerative diseases
  • Effect of diet on brain function
  • Role of neuroinflammation in neurodegenerative diseases and effect of natural antioxidants
  • Ethnopharmacological approach and evaluation on brain related disorders

Articles

  • Special Issue
  • - Volume 2017
  • - Article ID 5048432
  • - Editorial

Dietary Supplements/Antioxidants: Impact on Redox Status in Brain Diseases

Gilles J. Guillemin | Musthafa Mohamed Essa | ... | Thamilarasan Manivasagam
  • Special Issue
  • - Volume 2017
  • - Article ID 1716701
  • - Review Article

Multifarious Beneficial Effect of Nonessential Amino Acid, Glycine: A Review

Meerza Abdul Razak | Pathan Shajahan Begum | ... | Senthilkumar Rajagopal
  • Special Issue
  • - Volume 2017
  • - Article ID 7984327
  • - Research Article

The Neuroprotective Effects of Brazilian Green Propolis on Neurodegenerative Damage in Human Neuronal SH-SY5Y Cells

Junjun Ni | Zhou Wu | ... | Hiroshi Nakanishi
  • Special Issue
  • - Volume 2017
  • - Article ID 3279061
  • - Review Article

Protective Effect of Antioxidants on Neuronal Dysfunction and Plasticity in Huntington’s Disease

Thirunavukkarasu Velusamy | Archana S. Panneerselvam | ... | Mahesh Kandasamy
  • Special Issue
  • - Volume 2017
  • - Article ID 7039816
  • - Review Article

Nutrition and AGE-ing: Focusing on Alzheimer’s Disease

Giulia Abate | Mariagrazia Marziano | ... | Daniela Uberti
  • Special Issue
  • - Volume 2016
  • - Article ID 8590578
  • - Review Article

The Role of Reactive Oxygen Species in the Pathogenesis of Alzheimer’s Disease, Parkinson’s Disease, and Huntington’s Disease: A Mini Review

Shanmugam Manoharan | Gilles J. Guillemin | ... | Mohammed D. Akbar
  • Special Issue
  • - Volume 2016
  • - Article ID 6981595
  • - Research Article

Reversal of Trimethyltin-Induced Learning and Memory Deficits by 3,5-Dicaffeoylquinic Acid

Jin Yong Kang | Seon Kyeong Park | ... | Ho Jin Heo
  • Special Issue
  • - Volume 2016
  • - Article ID 9324085
  • - Review Article

Therapeutic Potential of Curcumin for the Treatment of Brain Tumors

Neil V. Klinger | Sandeep Mittal
  • Special Issue
  • - Volume 2016
  • - Article ID 1564257
  • - Research Article

Rosmarinic Acid and Melissa officinalis Extracts Differently Affect Glioblastoma Cells

Kristina Ramanauskiene | Raimondas Raudonis | Daiva Majiene
Oxidative Medicine and Cellular Longevity
 Journal metrics
Acceptance rate48%
Submission to final decision56 days
Acceptance to publication37 days
CiteScore7.300
Impact Factor5.076
 Submit

We are committed to sharing findings related to COVID-19 as quickly as possible. We will be providing unlimited waivers of publication charges for accepted research articles as well as case reports and case series related to COVID-19. Review articles are excluded from this waiver policy. Sign up here as a reviewer to help fast-track new submissions.