Oxidative Medicine and Cellular Longevity

Natural Products: Optimizing Cancer Treatment through Modulation of Redox Balance


Publishing date
01 Oct 2019
Status
Published
Submission deadline
31 May 2019

Lead Editor

1Research Center for Biosciences & Health Technologies (CBIOS), Lisboa, Portugal

2Institute for Biological Research “Siniša Stanković“, Belgrade, Serbia

3Research Center for Biosciences & Health Technologies (CBIOS), Lisbon, Portugal

4Instituto de Biologia Experimental e Tecnológica and Instituto de Tecnologia Química e Biológica (IBET-ITQB), Oeiras, Portugal


Natural Products: Optimizing Cancer Treatment through Modulation of Redox Balance

Description

Many natural products possess the ability to protect cells from oxidative stress and death. Consequently they are valuable for treating oxidative stress-related diseases. The overproduction of reactive oxygen species (ROS), oxidative stress, and inflammatory responses are involved in the pathogenesis of numerous human chronic diseases including cancer. Natural compounds are recognized for their healing properties from ancient time. Despite the bioactivity of natural compounds, its development towards clinics is usually hampered due to the unknown metabolism in humans and unidentified molecular mechanisms involved. Therefore, advanced and innovative studies of natural products should be performed to support their application in the prevention and treatment of oxidative stress-related human diseases and for the development of novel anticancer nature-inspired drugs.

The aim of this special issue is to emphasize the medicinal value of different natural products and their derivatives, particularly those which can be further developed for the prevention and treatment of oxidative-stress related diseases such as cancer. The articles within this special issue should provide information about efficacy and safety of different natural products and their potential to be developed as new anticancer drugs. Areas of interest include the interaction of natural products and/or their metabolites with intracellular targets associated with the pathology of oxidative stress-related diseases such as cancer.

Original research and review articles which describe the current state of the art of the topics of interest are welcome.

Potential topics include but are not limited to the following:

  • Natural products-induced molecular responses to mechanisms related to cancer: gene mutations, oxidative stress, cell metabolism, and hampered immunity
  • The role of natural products in the prevention and treatment of diseases related to oxidative stress and cancer (in vitro and in vivo studies)
  • Clinical studies to evaluate the impact of food supplements or nutraceuticals in oxidative stress and cancer biomarkers
  • Epidemiological studies evaluating preventive effects of natural products against development of cancer

Articles

  • Special Issue
  • - Volume 2020
  • - Article ID 2407074
  • - Editorial

Natural Products: Optimizing Cancer Treatment through Modulation of Redox Balance

Patrícia Rijo | Milica Pešić | ... | Cláudia N. Santos
  • Special Issue
  • - Volume 2020
  • - Article ID 6841581
  • - Review Article

Utilizing Melatonin to Alleviate Side Effects of Chemotherapy: A Potentially Good Partner for Treating Cancer with Ageing

Zhiqiang Ma | Liqun Xu | ... | Xiaolong Yan
  • Special Issue
  • - Volume 2019
  • - Article ID 2075614
  • - Review Article

Medicinal Plants in the Prevention and Treatment of Colon Cancer

Paola Aiello | Maedeh Sharghi | ... | Wesam Kooti
  • Special Issue
  • - Volume 2019
  • - Article ID 5820415
  • - Research Article

Tetramethylpyrazine Attenuates the Endotheliotoxicity and the Mitochondrial Dysfunction by Doxorubicin via 14-3-3γ/Bcl-2

Bin Yang | Hongwei Li | ... | Ming He
  • Special Issue
  • - Volume 2019
  • - Article ID 1805635
  • - Research Article

Polyphyllin VII Promotes Apoptosis and Autophagic Cell Death via ROS-Inhibited AKT Activity, and Sensitizes Glioma Cells to Temozolomide

Dejiang Pang | Chao Li | ... | Chao Huang
  • Special Issue
  • - Volume 2019
  • - Article ID 9165784
  • - Research Article

An Evaluation of the DNA-Protective Effects of Extracts from Menyanthes trifoliata L. Plants Derived from In Vitro Culture Associated with Redox Balance and Other Biological Activities

Tomasz Kowalczyk | Przemysław Sitarek | ... | Tomasz Śliwiński
  • Special Issue
  • - Volume 2019
  • - Article ID 3685264
  • - Review Article

Medicinal Plants from Brazilian Cerrado: Antioxidant and Anticancer Potential and Protection against Chemotherapy Toxicity

José Tarcísio de Giffoni de Carvalho | Débora da Silva Baldivia | ... | Edson Lucas dos Santos
  • Special Issue
  • - Volume 2019
  • - Article ID 9719730
  • - Research Article

Ocoxin Modulates Cancer Stem Cells and M2 Macrophage Polarization in Glioblastoma

Esther Hernández-SanMiguel | Ricardo Gargini | ... | Pilar Sánchez-Gómez
  • Special Issue
  • - Volume 2019
  • - Article ID 8307196
  • - Research Article

Antioxidant Effects of Satureja hortensis L. Attenuate the Anxiogenic Effect of Cisplatin in Rats

Igor Kumburovic | Dragica Selakovic | ... | Gvozden Rosic
  • Special Issue
  • - Volume 2019
  • - Article ID 1615758
  • - Research Article

Cytotoxic Effects of Artemisia annua L. and Pure Artemisinin on the D-17 Canine Osteosarcoma Cell Line

Gloria Isani | Martina Bertocchi | ... | Chiara Bernardini
Oxidative Medicine and Cellular Longevity
 Journal metrics
Acceptance rate42%
Submission to final decision56 days
Acceptance to publication37 days
CiteScore7.300
Impact Factor5.076
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