Magnesium and Other Biometals in Oxidative Medicine and Redox Biology
1Comenius University in Bratislava, Martin, Slovakia
2University of Glasgow, Glasgow, UK
3Case Western Reserve University, Cleveland, USA
4University of Palermo, Palermo, Italy
Magnesium and Other Biometals in Oxidative Medicine and Redox Biology
Description
Research on magnesium (Mg) and other biometals (BM) in biology and translational medicine is gaining momentum. Plethora of works defined importance of Mg and other BM in complex cellular physiology. Plentiful reactions essential for cellular homeostasis depend on presence of Mg and other BM in cells and their milieu.
Magnesium, zinc, copper, manganese, and molybdenum are essential for mitochondrial homeostasis, normal redox homeostasis, and antioxidant signaling. Disturbances in their homeostasis may lead to chronic degenerative ailments hallmarked by increased levels of oxidative stress that negatively influence every aspect of cellular physiology (e.g., proliferation, cellular energetics, solute trafficking, biogenesis and degradation (autophagy/mitophagy) of organelles and subcellular compartments, and turnover of biomacromolecules).
Given the importance of Mg and other BM, we solicit high quality original research papers, excellent review papers, and clinical studies.
Potential topics include but are not limited to the following:
- Mg and other BM in redox biology with special focus on bioenergetics, mitochondrial homeostasis (autophagy/mitophagy), cellular signaling, transport of solutes, base excision DNA repair, cell division, and cell proliferation
- Mg and other BM in oxidative medicine with special focus on cardiovascular complications, hypertension, endothelial dysfunction, vascular calcification, vascular dementia, and so forth
- Mg and other BM in oxidative medicine with special focus on metabolic disorders (e.g., obesity and diabetes) and neurodegenerative diseases (e.g., Parkinson’s disease)
- Mg and other BM in oxidative medicine with special focus on psychiatric diseases (e.g., schizophrenia)
- Mg and other BM in oxidative medicine with special focus on cancer
- Manganese, oxidative stress, and neurodegeneration (manganism); BM (Mn, Zn, and Fe) and oxidative stress in childhood-onset parkinsonism-dystonia
- Biodegradable Mg-based alloys and oxidative stress; challenges and achievements in implantology
- Oxidative stress, Mg, and other BM in ageing
- BM, oxidative stress, and antioxidative defense mechanisms in chronobiology and chronomedicine (regulation of circadian rhythms)