Oxidative Medicine and Cellular Longevity

Where Are We Now with Translating Biomarkers of Oxidative Stress into Clinical Practice?


Publishing date
01 Nov 2019
Status
Closed
Submission deadline
05 Jul 2019

1University of Belgrade, Belgrade, Serbia

2National Autonomous University of Mexico, Mexico City, Mexico

3University of Camerino, Camerino, Italy

This issue is now closed for submissions.
More articles will be published in the near future.

Where Are We Now with Translating Biomarkers of Oxidative Stress into Clinical Practice?

This issue is now closed for submissions.
More articles will be published in the near future.

Description

Although many studies have shown that oxidative stress is significantly involved in the pathogenesis of many acute and chronic diseases, the implementation of specific biomarkers of oxidative stress in routine clinical practice is still limited. Before using a biomarker of oxidative stress in biological fluids, it must be validated. The validation process of a biomarker of oxidative stress is faced with several serious challenges. From an analytical point of view, it is important to validate methods that could be applicable in routine clinical practice, i.e., being fast, simple, and cost-effective. Validation of diagnostic accuracy of biomarkers of oxidative stress includes the development of a construct and establishing diagnostic sensitivity and specificity. In this regard, the reference intervals or cut-off values of biomarkers of oxidative stress need be established too.

The ultimate goal of introducing biomarkers of oxidative stress in clinical practice is the prevention and control of oxidative stress-related diseases. The screening of biomarkers of oxidative stress may be potentially significant in the prevention of congenital sensitivity to oxidative stress and of diseases in which oxidative stress plays a causative role.

The aim of this special issue is to present the current state-of-the-art on translation of oxidative stress biomarkers to clinical practice and its usefulness in prevention, detection, and monitoring diseases caused by oxidative stress. Thus, we invite researchers who are concerned with the validation of biomarkers of oxidative stress to present their results. In particular, we invite researchers to present studies on the development and application of oxidative stress biomarkers in routine clinical practice. Original research articles, review articles, and meta-analyzing studies are welcome.

Potential topics include but are not limited to the following:

  • Development of oxidative stress biomarkers in biological fluids
  • Relevance of oxidative stress biomarkers for routine clinical practice
  • Oxidative stress assays suitable for routine clinical practice
  • Reference intervals and cut-off values of oxidative stress biomarkers
  • Oxidative stress biomarkers in interventional studies of antioxidant therapy
  • Meta-analyses of implementation biomarkers of oxidative stress in clinical practice
Oxidative Medicine and Cellular Longevity
 Journal metrics
Acceptance rate48%
Submission to final decision74 days
Acceptance to publication36 days
CiteScore4.520
Impact Factor4.868
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