Oxidative Medicine and Cellular Longevity

Oxidative Stress in Cardiovascular Pathologies: Genetics, Cellular, and Molecular Mechanisms and Future Antioxidant Therapies


Publishing date
24 Aug 2012
Status
Published
Submission deadline
06 Apr 2012

Lead Editor

1Department of Molecular Biology and Pharmacology, Institute of Cellular Biology and Pathology “Nicolae Simionescu”, 8 B.P. Hasdeu Street, Bucharest, Romania

2Division of Cardiovascular Sciences, Center for Applied Medical Research, University of Navarra, Pio XII 55, 31008 Pamplona, Spain

3Vascular Research Laboratory, Fundación Jiménez Diaz, Avenida Reyes Católicos 2, 28040 Madrid, Spain; Autonomous University of Madrid, 28049 Madrid, Spain


Oxidative Stress in Cardiovascular Pathologies: Genetics, Cellular, and Molecular Mechanisms and Future Antioxidant Therapies

Description

Eukaryotic cells constantly face the formation of reactive oxygen species (ROS) as a result of their aerobic metabolism. ROS play an important role in the regulation of signal transduction pathways and gene expression but its overproduction is acutely harmful to cells, particularly in cardiovascular diseases by a mechanism that is not fully understood. Therefore, uncovering the molecular mechanisms of ROS formation and function is a prerequisite of an effective antioxidative stress therapy. Oxidative stress is a common occurrence in most pathologies, that is, atherosclerosis, hypertension, diabetes, obesity, abdominal aortic aneurism, neurodegenerative diseases, cancer, and so forth. Despite the numerous existing data, an open area in the field is the “fine-tuning” mechanisms of oxidative stress-induced vascular inflammation and injury. Thus, the topic of this special issue focuses on the recent advances in experimental and clinical aspects of oxidative stress in cardiovascular disorders.

We invite researchers to contribute original research articles as well as review articles that will stimulate the ongoing efforts to identify the basic molecular mechanisms regulating the oxidative stress that will be used to find ways to manage its occurrence and correct its adverse effects. Potential topics include, but are not limited to:

  • Reactive oxygen species formation and function in cardiovascular system
  • Antioxidant mechanisms
  • Cellular and molecular aspects of oxidative stress in cardiovascular cells
  • Experimental models and approaches for the study of oxidative stress
  • Biomarkers of oxidative stress
  • Genetics of oxidative stress
  • Clinical aspects of oxidative stress in cardiovascular diseases
  • Recent advances in antioxidant therapies

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/oximed/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2012
  • - Article ID 373450
  • - Editorial

Oxidative Stress in Cardiovascular Pathologies: Genetics, Cellular, and Molecular Mechanisms and Future Antioxidant Therapies

Adrian Manea | Ana Fortuno | Jose Luis Martin-Ventura
  • Special Issue
  • - Volume 2012
  • - Article ID 542042
  • - Research Article

Sodium-Glucose Cotransporter Inhibition Prevents Oxidative Stress in the Kidney of Diabetic Rats

Horacio Osorio | Israel Coronel | ... | Bruno Escalante
  • Special Issue
  • - Volume 2012
  • - Article ID 381763
  • - Research Article

Oxygen Concentration-Dependent Oxidative Stress Levels in Rats

Fumiko Nagatomo | Hidemi Fujino | ... | Akihiko Ishihara
  • Special Issue
  • - Volume 2012
  • - Article ID 139327
  • - Research Article

Intensification of Doxorubicin-Related Oxidative Stress in the Heart by Hypothyroidism Is Not Related to the Expression of Cytochrome P450 NADPH-Reductase and Inducible Nitric Oxide Synthase, As Well As Activity of Xanthine Oxidase

Jaroslaw Dudka | Franciszek Burdan | ... | Wlodzimierz Matysiak
  • Special Issue
  • - Volume 2012
  • - Article ID 329743
  • - Research Article

Evaluation of Oxidative Stress and Antioxidant Status in Diabetic and Hypertensive Women during Labor

Mashael M. Al-Shebly | Mahmoud A. Mansour
  • Special Issue
  • - Volume 2012
  • - Article ID 134723
  • - Research Article

Effect of Antioxidant Mineral Elements Supplementation in the Treatment of Hypertension in Albino Rats

S. A. Muhammad | L. S. Bilbis | ... | Y. Adamu
  • Special Issue
  • - Volume 2012
  • - Article ID 761710
  • - Research Article

Protective Effects of Aspirin from Cardiac Hypertrophy and Oxidative Stress in Cardiomyopathic Hamsters

Rong Wu | David Yin | ... | Helene Girouard
  • Special Issue
  • - Volume 2012
  • - Article ID 232464
  • - Review Article

Cell Stress Proteins in Atherothrombosis

Julio Madrigal-Matute | Roxana Martinez-Pinna | ... | Jose Luis Martin-Ventura
  • Special Issue
  • - Volume 2012
  • - Article ID 726940
  • - Research Article

Blockade of TGF- 1 Signalling Inhibits Cardiac NADPH Oxidase Overactivity in Hypertensive Rats

José Luis Miguel-Carrasco | Ana Baltanás | ... | Guillermo Zalba
  • Special Issue
  • - Volume 2012
  • - Article ID 418748
  • - Research Article

Ginkgo Biloba Extract EGB761 Protects against Aging-Associated Diastolic Dysfunction in Cardiomyocytes of D-Galactose-Induced Aging Rat

Jing Liu | Junhong Wang | ... | Hui Wang
Oxidative Medicine and Cellular Longevity
 Journal metrics
Acceptance rate48%
Submission to final decision56 days
Acceptance to publication37 days
CiteScore7.300
Impact Factor5.076
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