Oxidative Medicine and Cellular Longevity

Targeting Redox Mechanisms for Novel Cardiopulmonary Therapeutics


Publishing date
01 Aug 2020
Status
Closed
Submission deadline
03 Apr 2020

1Baylor College of Medicine, Houston, USA

2Ohio State University, Columbus, USA

3Florida International University, Miami, USA

This issue is now closed for submissions.
More articles will be published in the near future.

Targeting Redox Mechanisms for Novel Cardiopulmonary Therapeutics

This issue is now closed for submissions.
More articles will be published in the near future.

Description

Extensive research in recent years has suggested that low levels of reactive oxygen species (ROS) are essential for redox signaling and normal physiological health, while supraphysiological levels can lead to disrupted signaling and cellular injury. Many human diseases are associated with or exacerbated by oxidative stress and novel approaches to mitigate oxidative stress are needed for prevention and/or treatment. Roles for redox mechanisms have been defined in the pathophysiology of pulmonary diseases such as asthma, bronchopulmonary dysplasia (BPD), acute respiratory distress syndrome (ARDS), pulmonary hypertension, and cardiovascular diseases, such as atherosclerosis and ischemia/reperfusion injury, making redox-related processes a logical target for prevention and therapeutic development.

We invite authors to contribute original research articles as well as review articles that will illustrate and stimulate the rapid advances that are taking place in the field of preventative/therapeutic development to address redox mechanisms and human diseases. We are particularly interested in manuscripts describing studies targeting of redox signaling pathways for the treatment and prevention of cardiopulmonary diseases using animal or in vitro models.

Potential topics include but are not limited to the following:

  • Pulmonary diseases such as asthma, BPD, ARDS, and pulmonary hypertension
  • Cardiovascular diseases such as atherosclerosis and ischemia/reperfusion injury
  • ROS and redox signaling in myocardial ischemia-reperfusion injury and cardioprotection
  • Age-related cardiovascular disease using redox stress markers

Articles

  • Special Issue
  • - Volume 2020
  • - Article ID 3598715
  • - Research Article

Follistatin-Like 1 Protects against Doxorubicin-Induced Cardiomyopathy through Upregulation of Nrf2

Yintao Zhao | Jingjing Sun | ... | Yuan Liu
  • Special Issue
  • - Volume 2020
  • - Article ID 6120194
  • - Research Article

Dexmedetomidine Ameliorates Lung Injury Induced by Intestinal Ischemia/Reperfusion by Upregulating Cannabinoid Receptor 2, Followed by the Activation of the Phosphatidylinositol 3-Kinase/Akt Pathway

Meng Chen | Xue-Tao Yan | ... | Xiang-Hu He
  • Special Issue
  • - Volume 2020
  • - Article ID 6973636
  • - Research Article

Combination of Dichloroacetate and Atorvastatin Regulates Excessive Proliferation and Oxidative Stress in Pulmonary Arterial Hypertension Development via p38 Signaling

Tangzhiming Li | Suqi Li | ... | Zaixin Yu
  • Special Issue
  • - Volume 2020
  • - Article ID 7308736
  • - Review Article

The Research Progress of Vascular Macrophages and Atherosclerosis

Yeqing Tong | Li Cai | ... | Jinquan Cheng
  • Special Issue
  • - Volume 2020
  • - Article ID 5347204
  • - Research Article

Asiatic Acid Protects against Doxorubicin-Induced Cardiotoxicity in Mice

Xiaoping Hu | Baijun Li | ... | Bin Shen
  • Special Issue
  • - Volume 2020
  • - Article ID 7606938
  • - Research Article

DHA Supplementation Attenuates MI-Induced LV Matrix Remodeling and Dysfunction in Mice

I. Habicht | G. Mohsen | ... | M. Velten
  • Special Issue
  • - Volume 2020
  • - Article ID 5751768
  • - Research Article

The Role of DNMT and HDACs in the Fetal Programming of Hypertension by Glucocorticoids

J. Lamothe | S. Khurana | ... | T. C. Tai
  • Special Issue
  • - Volume 2020
  • - Article ID 9081813
  • - Review Article

Potential Role of Antioxidants as Adjunctive Therapy in Chagas Disease

Juana P. Sánchez-Villamil | Paula K. Bautista-Niño | ... | Nisha J. Garg
  • Special Issue
  • - Volume 2020
  • - Article ID 2563764
  • - Research Article

Norepinephrine Induces Lung Microvascular Endothelial Cell Death by NADPH Oxidase-Dependent Activation of Caspase-3

Andreia Z. Chignalia | Guy Weinberg | Randal O. Dull
  • Special Issue
  • - Volume 2020
  • - Article ID 1841527
  • - Research Article

Resveratrol Prevents Right Ventricle Remodeling and Dysfunction in Monocrotaline-Induced Pulmonary Arterial Hypertension with a Limited Improvement in the Lung Vasculature

Eduardo Vázquez-Garza | Judith Bernal-Ramírez | ... | Gerardo García-Rivas
Oxidative Medicine and Cellular Longevity
 Journal metrics
Acceptance rate48%
Submission to final decision56 days
Acceptance to publication37 days
CiteScore7.300
Impact Factor5.076
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