Oxidative Medicine and Cellular Longevity

Targeting Redox Mechanisms for Novel Cardiopulmonary Therapeutics


Publishing date
01 Aug 2020
Status
Closed
Submission deadline
03 Apr 2020

1Baylor College of Medicine, Houston, USA

2Ohio State University, Columbus, USA

3Florida International University, Miami, USA

This issue is now closed for submissions.
More articles will be published in the near future.

Targeting Redox Mechanisms for Novel Cardiopulmonary Therapeutics

This issue is now closed for submissions.
More articles will be published in the near future.

Description

Extensive research in recent years has suggested that low levels of reactive oxygen species (ROS) are essential for redox signaling and normal physiological health, while supraphysiological levels can lead to disrupted signaling and cellular injury. Many human diseases are associated with or exacerbated by oxidative stress and novel approaches to mitigate oxidative stress are needed for prevention and/or treatment. Roles for redox mechanisms have been defined in the pathophysiology of pulmonary diseases such as asthma, bronchopulmonary dysplasia (BPD), acute respiratory distress syndrome (ARDS), pulmonary hypertension, and cardiovascular diseases, such as atherosclerosis and ischemia/reperfusion injury, making redox-related processes a logical target for prevention and therapeutic development.

We invite authors to contribute original research articles as well as review articles that will illustrate and stimulate the rapid advances that are taking place in the field of preventative/therapeutic development to address redox mechanisms and human diseases. We are particularly interested in manuscripts describing studies targeting of redox signaling pathways for the treatment and prevention of cardiopulmonary diseases using animal or in vitro models.

Potential topics include but are not limited to the following:

  • Pulmonary diseases such as asthma, BPD, ARDS, and pulmonary hypertension
  • Cardiovascular diseases such as atherosclerosis and ischemia/reperfusion injury
  • ROS and redox signaling in myocardial ischemia-reperfusion injury and cardioprotection
  • Age-related cardiovascular disease using redox stress markers

Articles

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  • - Article ID 5148503
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Virgin Coconut Oil Supplementation Prevents Airway Hyperreactivity of Guinea Pigs with Chronic Allergic Lung Inflammation by Antioxidant Mechanism

Luiz Henrique C. Vasconcelos | Maria da Conceição C. Silva | ... | Bagnólia A. da Silva
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  • - Volume 2020
  • - Article ID 1535201
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Melatonin Ameliorates MI-Induced Cardiac Remodeling and Apoptosis through a JNK/p53-Dependent Mechanism in Diabetes Mellitus

Linhe Lu | Jipeng Ma | ... | Jian Yang
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  • - Volume 2019
  • - Article ID 7595126
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Toxic Acetaminophen Exposure Induces Distal Lung ER Stress, Proinflammatory Signaling, and Emphysematous Changes in the Adult Murine Lung

Jeryl Sandoval | David J. Orlicky | ... | Clyde J. Wright
  • Special Issue
  • - Volume 2019
  • - Article ID 8327486
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Role of HIF-1α-miR30a-Snai1 Axis in Neonatal Hyperoxic Lung Injury

Yuhao Zhang | Xiaoyu Dong | Krithika Lingappan
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  • - Volume 2019
  • - Article ID 5204218
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Cell Type- and Exposure-Specific Modulation of CD63/CD81-Positive and Tissue Factor-Positive Extracellular Vesicle Release in response to Respiratory Toxicants

Frank R. M. Stassen | Pascalle H. van Eijck | ... | Birke J. Benedikter
  • Special Issue
  • - Volume 2019
  • - Article ID 7901735
  • - Research Article

Protection against Doxorubicin-Induced Cytotoxicity by Geniposide Involves AMPKα Signaling Pathway

Yan-Yan Meng | Yu-Pei Yuan | ... | Qi-Zhu Tang
  • Special Issue
  • - Volume 2019
  • - Article ID 9719723
  • - Research Article

miR-25 Promotes Cell Proliferation, Migration, and Invasion of Non-Small-Cell Lung Cancer by Targeting the LATS2/YAP Signaling Pathway

Tangwei Wu | Hui Hu | ... | Zhongxin Lu
  • Special Issue
  • - Volume 2019
  • - Article ID 7945983
  • - Research Article

Thioredoxin Reductase-1 Inhibition Augments Endogenous Glutathione-Dependent Antioxidant Responses in Experimental Bronchopulmonary Dysplasia

Stephanie B. Wall | Rachael Wood | ... | Trent E. Tipple
Oxidative Medicine and Cellular Longevity
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Acceptance rate48%
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Acceptance to publication37 days
CiteScore7.900
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Article of the Year Award: Outstanding research contributions of 2020, as selected by our Chief Editors. Read the winning articles.