Neurodegeneration, Neurogenesis, and Oxidative Stress 2015
1Ecole Normale Supérieure, Paris, France
2University of Pau, Pau, France
3Instituto Tecnologia Quimica e Biologica (ITQB), Oeiras, Portugal
Neurodegeneration, Neurogenesis, and Oxidative Stress 2015
Description
Oxidative stress is implicated in the pathophysiology of a wide variety of neurodegenerative disorders, including Parkinson’s disease, Alzheimer’s disease, Friedreich’s ataxia, amyotrophic lateral sclerosis, and stroke. Neural stem cells persist in the adult brain and continue to produce neurons throughout life. However, neurogenesis is impaired in inflammation-associated diseases by mechanisms poorly understood. In addition, the contribution of neurogenesis impairment to disease progression is not clear. Over the last years, stem cell technologies have made this system become an increasingly attractive target for the development of neurodegenerative disease therapies. Thus, further investigation in this subject will clarify several aspects of the implication of oxidative stress and inflammation in neurodegeneration and neurogenesis and contribute to the development of future therapies for neurodegenerative diseases.
We invite authors to submit original research and review articles that seek to refine the understanding of the role of oxidative and nitrosative stress, calcium, mitochondrial functions, and inflammation in the pathophysiology of neurodegenerative diseases and neurogenesis.
Potential topics include, but are not limited to:
- Research in the function of mitochondria, reactive oxygen species, and nitric oxide in neurogenesis and neuron survival
- Advances in the role of oxidative stress in neurodegeneration and neurogenesis
- Role of inflammation in neurodegeneration and neurogenesis
- Role of microglia and oxidative stress in the neurogenic zones of the brain
- Research on neuronal and glial proteins involved in neurodegeneration or neurogenesis
- Recent developments in stem cell therapies for neurodegenerative diseases