Oxidative Medicine and Cellular Longevity

Oxidative Stress in Metabolic Disorders: Pathogenesis, Prevention, and Therapeutics


Status
Published

Lead Editor

1Central University of Gujarat, Gandhinagar, India

2Jaypee Institute of Information Technology, Uttar Pradesh, India

3University of Colorado Denver, Aurora, USA

4Florida State University, Tallahassee, USA

5USA Mitchell Cancer Institute, Alabama, USA


Oxidative Stress in Metabolic Disorders: Pathogenesis, Prevention, and Therapeutics

Description

Metabolic disorders involve disruption of normal metabolic processes and energy disbalance leading to many pathophysiological changes including obesity, dyslipidaemia, diabetes, and cardiovascular disease collectively termed as metabolic syndrome. Obesity is also linked with increased risks of cancers. Recent studies suggest that metabolic syndrome is associated with increased oxidative stress, which may be at the core of developing cellular dysfunction and associated disorders. Oxidative stress emanates from loss of balance between the generation and scavenging of reactive oxygen species (ROS) which leads to oxidative modifications of biomolecules including lipids, carbohydrates, proteins, and nucleic acids. The damaged biomolecules, being highly reactive, can further promote cell and tissue dysfunction leading to pathogenesis. The emerging correlation between oxidative stress and metabolic disorders is important to understand which may lead to identification of novel biomarkers, molecular targets, and drug designing for prevention and therapeutic intervention. Recent advancement in the understanding of oxidative damages to cells has provided better tools which may be helpful in unravelling the intricate relationship between oxidative stress and metabolic disorders. The current intensive research in this area is yielding novel findings which must be presented and consolidated to enhance the overall understanding.

We invite investigators and scholars to contribute original research paper and review article in our special issue in the following subarea of “oxidative stress in metabolic disorders.”

Potential topics include, but are not limited to:

  • Redox imbalance, metabolic disorders, and signalling mechanisms
  • Mechanisms of production and types of reactive species in metabolic disorders
  • Intricate link between inflammation, oxidative stress, and metabolic disorders
  • Mitochondrial oxidative stress in metabolic disorders
  • Interplay between oxidative stress, endoplasmic reticulum (ER) stress, and metabolic disorders
  • Novel molecular targets with translational potential
  • Novel and relevant disease models to study oxidative stress mechanisms in metabolic disorders
  • Preventive and therapeutic agents/drugs
  • Technical advancements for investigating oxidative stress induced metabolic disorders

Articles

  • Special Issue
  • - Volume 2016
  • - Article ID 9137629
  • - Editorial

Oxidative Stress in Metabolic Disorders: Pathogenesis, Prevention, and Therapeutics

Umesh C. S. Yadav | Vibha Rani | ... | Komaraiah Palle
  • Special Issue
  • - Volume 2016
  • - Article ID 8524267
  • - Research Article

Differential Mitochondrial Adaptation in Primary Vascular Smooth Muscle Cells from a Diabetic Rat Model

Amy C. Keller | Leslie A. Knaub | ... | Jane E. B. Reusch
  • Special Issue
  • - Volume 2016
  • - Article ID 3218605
  • - Review Article

Lycopene Deficiency in Ageing and Cardiovascular Disease

Ivan M. Petyaev
  • Special Issue
  • - Volume 2016
  • - Article ID 1943918
  • - Research Article

Diabetes-Induced Oxidative Stress in Endothelial Progenitor Cells May Be Sustained by a Positive Feedback Loop Involving High Mobility Group Box-1

Han Wu | Ran Li | ... | Biao Xu
  • Special Issue
  • - Volume 2016
  • - Article ID 9618092
  • - Review Article

Role of Galectin-3 in Obesity and Impaired Glucose Homeostasis

Stefano Menini | Carla Iacobini | ... | Giuseppe Pugliese
  • Special Issue
  • - Volume 2016
  • - Article ID 4528906
  • - Research Article

Targeting Pin1 Protects Mouse Cardiomyocytes from High-Dose Alcohol-Induced Apoptosis

Yuehong Wang | Zizhuo Li | ... | Weimin Li
  • Special Issue
  • - Volume 2016
  • - Article ID 5136937
  • - Research Article

PON-1 Activity and Plasma 8-Isoprostane Concentration in Patients with Angiographically Proven Coronary Artery Disease

Agnieszka Kuchta | Adrian Strzelecki | ... | Maciej Jankowski
  • Special Issue
  • - Volume 2016
  • - Article ID 2352361
  • - Research Article

Markers of Antioxidant Defense in Patients with Type 2 Diabetes

K. Gawlik | J. W. Naskalski | ... | B. Solnica
  • Special Issue
  • - Volume 2015
  • - Article ID 214836
  • - Research Article

EGCG Attenuates Uric Acid-Induced Inflammatory and Oxidative Stress Responses by Medicating the NOTCH Pathway

Hua Xie | Jianqin Sun | ... | Yan Wang
Oxidative Medicine and Cellular Longevity
 Journal metrics
Acceptance rate42%
Submission to final decision56 days
Acceptance to publication39 days
CiteScore7.300
Impact Factor5.076
 Submit

We are committed to sharing findings related to COVID-19 as quickly and safely as possible. Any author submitting a COVID-19 paper should notify us at help@hindawi.com to ensure their research is fast-tracked and made available on a preprint server as soon as possible. We will be providing unlimited waivers of publication charges for accepted articles related to COVID-19. Sign up here as a reviewer to help fast-track new submissions.