Oxidative Medicine and Cellular Longevity

Oxidative Stress in Neurodegenerative Diseases and Ageing


Publishing date
13 Jul 2012
Status
Published
Submission deadline
13 Jan 2012

1Department of Biochemistry, Chemistry Institute, Federal University of Rio de Janeiro, 21941-909 Rio de Janeiro, Brazil

2Department of Pathophysiology, Poznan University of Medical Sciences, 60-781 Poznan, Poland

3Genomics and Stress Laboratory, Institute of Chemistry and Biological Technology (ITQB), 2780-157 Oeiras, Portugal


Oxidative Stress in Neurodegenerative Diseases and Ageing

Description

Oxidative stress can be characterized by an excessive increase in the generation of reactive oxygen species (ROS). Although several important biological functions have been attributed to ROS, harmful effects can take place when high levels of these reactive molecules are encountered in cells. Counteracting the toxic side effect of ROS, antioxidant defense systems have been evolved in cells to eliminate or repair oxidatively damaged macromolecules. The complex balance between ROS generation and detoxification is dependent on an intricate process named redox regulation. In addition, oxidative stress has been pointed out as either a cause or a consequence of several diseases such as cancer, metal induced diseases, neurodegenerative disorders, and ageing. Thus, the knowledge and understanding of the mechanism by which oxidative stress triggers such disorders is the focus of modern life sciences.

We, therefore, invite authors to contribute with high-quality original research as well as review articles that will explore the relationship between oxidative stress, neurodegenerative disorders, and ageing. We are interested in articles focusing on the exploring mechanisms of ROS generation, responsive genes and signaling pathways, detection of new oxidative stress biomarkers associated with neuron degeneration and ageing, current concepts in the treatment of the oxidative stress as well as neurodegeneration, new insights into neurodegenerative diseases using different experimental models, advances in molecular diagnostics associated with neurodegeneration. Potential topics include, but are not limited to:

  • Recent developments in the research of oxidative stress related to neurodegenerative diseases and ageing
  • New biological models for studies on the oxidative stress, neurodegenerative diseases, and ageing
  • Understanding oxidative stress emergence
  • Advances in genetics and molecular mechanisms of neurodegenerative diseases and ageing
  • Identification of the new factors involved in oxidative stress response and neurodegenerative diseases
  • Focus on the novel oxidative biomarkers of ROS-induced cell damage and toxicity in neurodegenerative diseases and ageing
  • Recent advances in redox regulation of gene expression
  • Current strategies to reduce the development of the oxidative stress in neurodegeneration and ageing

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/oximed/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2012
  • - Article ID 796360
  • - Editorial

Oxidative Stress in Neurodegenerative Diseases and Ageing

Marcos D. Pereira | Krzysztof Ksiazek | Regina Menezes
  • Special Issue
  • - Volume 2012
  • - Article ID 795259
  • - Review Article

Oxidative Stress and Epilepsy: Literature Review

Carlos Clayton Torres Aguiar | Anália Barbosa Almeida | ... | Silvania Maria Mendes Vasconcelos
  • Special Issue
  • - Volume 2012
  • - Article ID 624925
  • - Review Article

Oxidative Stress in Genetic Mouse Models of Parkinson’s Disease

Mustafa Varçin | Eduard Bentea | ... | Sophie Sarre
  • Special Issue
  • - Volume 2012
  • - Article ID 718976
  • - Review Article

Alterations in Nitric Oxide Synthase in the Aged CNS

Junyang Jung | Changhyun Na | Youngbuhm Huh
  • Special Issue
  • - Volume 2012
  • - Article ID 740280
  • - Research Article

Reactive Oxygen Species Formation and Apoptosis in Human Peripheral Blood Mononuclear Cell Induced by 900 MHz Mobile Phone Radiation

Yao-Sheng Lu | Bao-Tian Huang | Yao-Xiong Huang
  • Special Issue
  • - Volume 2012
  • - Article ID 353152
  • - Review Article

Molecular Hydrogen as an Emerging Therapeutic Medical Gas for Neurodegenerative and Other Diseases

Kinji Ohno | Mikako Ito | ... | Masafumi Ito
  • Special Issue
  • - Volume 2012
  • - Article ID 928421
  • - Research Article

Association of Base Excision Repair Gene Polymorphisms with ESRD Risk in a Chinese Population

Zhenming Cai | Huimei Chen | ... | Yaping Wang
  • Special Issue
  • - Volume 2012
  • - Article ID 205713
  • - Review Article

Oxidative Stress: A Pathogenic Mechanism for Niemann-Pick Type C Disease

Mary Carmen Vázquez | Elisa Balboa | ... | Silvana Zanlungo
  • Special Issue
  • - Volume 2012
  • - Article ID 132146
  • - Review Article

Oxidative Stress in Alzheimer's and Parkinson's Diseases: Insights from the Yeast Saccharomyces cerevisiae

Catarina Pimentel | Liliana Batista-Nascimento | ... | Regina A. Menezes
  • Special Issue
  • - Volume 2012
  • - Article ID 128647
  • - Review Article

Iron and Neurodegeneration: From Cellular Homeostasis to Disease

Liliana Batista-Nascimento | Catarina Pimentel | ... | Claudina Rodrigues-Pousada
Oxidative Medicine and Cellular Longevity
 Journal metrics
Acceptance rate44%
Submission to final decision79 days
Acceptance to publication45 days
CiteScore4.520
Impact Factor4.868
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