Oxidative Medicine and Cellular Longevity

Nucleic Acid Oxidation in Human Health and Disease


Publishing date
20 Dec 2013
Status
Published
Submission deadline
02 Aug 2013

Lead Editor

1Department of Occupational Safety and Health, Chung Shan Medical University, Taichung 402, Taiwan

2Laboratory of Genetic Ecotoxicology, Institute of Experimental Medicine, Academy of Sciences of the Czech Republic, Videnska 1083, 142 20 Prague, Czech Republic

3Centre for Radiation Protection Research, Department of Genetics, Microbiology and Toxicology, Stockholm University, 10691 Stockholm, Sweden

4School of Community and Environmental Health, College of Health Sciences, Old Dominion University, Norfolk, VA 23529, USA

5Department of Public Health, Chung Shan Medical University, Taichung 402, Taiwan


Nucleic Acid Oxidation in Human Health and Disease

Description

Growing scientific evidence suggests that oxidative stress plays an important role in human health and disease. Under oxidative stress, the excess levels of reactive oxygen species (ROS) may lead to modification of cellular nucleic acids. Oxidatively damaged DNA has been recognized in association with the development of aging, cancer, and some degenerative diseases. Meanwhile, oxidative modification of RNA, an emerging area, has received attention over the past decade and has been found to cause disturbances in the translational process and impairment in protein synthesis, which can result in cell deterioration or even cell death. Particularly, its potential role involved in the process of aging and neurodegenerative disorders has been recently highlighted in human brain tissue and experimental models.

We invite authors to submit original research and review articles that explore aspects of nucleic acid oxidation products in human disease and health. Potential topics include, but are not limited to:

  • Identification of new DNA/RNA oxidation products
  • Novel methods for quantification of nucleic acid oxidation products
  • Elucidating the role of nucleic acid oxidation products in the development of human disease
  • Identification/application of nucleic acid oxidation products as biomarkers in human disease or health care
  • Identification/application of nucleic acid oxidation products as biomarkers for assessing efficacy of therapy
  • Changes in oxidatively damaged DNA/RNA repair during aging and disease

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/oximed/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/oximed/naohd/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2013
  • - Article ID 925804
  • - Review Article

Phytoagents for Cancer Management: Regulation of Nucleic Acid Oxidation, ROS, and Related Mechanisms

Wai-Leng Lee | Jing-Ying Huang | Lie-Fen Shyur
  • Special Issue
  • - Volume 2013
  • - Article ID 368651
  • - Editorial

Nucleic Acid Oxidation in Human Health and Disease

Mu-Rong Chao | Pavel Rossner | ... | Chiung-Wen Hu
  • Special Issue
  • - Volume 2013
  • - Article ID 387014
  • - Review Article

DNA Damage in Inflammation-Related Carcinogenesis and Cancer Stem Cells

Shiho Ohnishi | Ning Ma | ... | Shosuke Kawanishi
  • Special Issue
  • - Volume 2013
  • - Article ID 237583
  • - Research Article

Is the Oxidative DNA Damage Level of Human Lymphocyte Correlated with the Antioxidant Capacity of Serum or the Base Excision Repair Activity of Lymphocyte?

Yi-Chih Tsai | Pei-Yi Li | ... | Yin-Chang Liu
  • Special Issue
  • - Volume 2013
  • - Article ID 474203
  • - Research Article

Oxidative Stress Is Involved in the Pathogenesis of Keshan Disease (an Endemic Dilated Cardiomyopathy) in China

Junrui Pei | Wenqi Fu | ... | Yang Liu
  • Special Issue
  • - Volume 2013
  • - Article ID 301982
  • - Review Article

Oxidative Stress and Nucleic Acid Oxidation in Patients with Chronic Kidney Disease

Chih-Chien Sung | Yu-Chuan Hsu | ... | Chia-Chao Wu
Oxidative Medicine and Cellular Longevity
 Journal metrics
Acceptance rate48%
Submission to final decision56 days
Acceptance to publication37 days
CiteScore7.300
Impact Factor5.076
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