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Nucleic Acid Oxidation in Human Health and Disease

Call for Papers

Growing scientific evidence suggests that oxidative stress plays an important role in human health and disease. Under oxidative stress, the excess levels of reactive oxygen species (ROS) may lead to modification of cellular nucleic acids. Oxidatively damaged DNA has been recognized in association with the development of aging, cancer, and some degenerative diseases. Meanwhile, oxidative modification of RNA, an emerging area, has received attention over the past decade and has been found to cause disturbances in the translational process and impairment in protein synthesis, which can result in cell deterioration or even cell death. Particularly, its potential role involved in the process of aging and neurodegenerative disorders has been recently highlighted in human brain tissue and experimental models.

We invite authors to submit original research and review articles that explore aspects of nucleic acid oxidation products in human disease and health. Potential topics include, but are not limited to:

  • Identification of new DNA/RNA oxidation products
  • Novel methods for quantification of nucleic acid oxidation products
  • Elucidating the role of nucleic acid oxidation products in the development of human disease
  • Identification/application of nucleic acid oxidation products as biomarkers in human disease or health care
  • Identification/application of nucleic acid oxidation products as biomarkers for assessing efficacy of therapy
  • Changes in oxidatively damaged DNA/RNA repair during aging and disease

Before submission authors should carefully read over the journal's Author Guidelines, which are located at Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at according to the following timetable:

Manuscript DueFriday, 2 August 2013
First Round of ReviewsFriday, 25 October 2013
Publication DateFriday, 20 December 2013

Lead Guest Editor

  • Mu-Rong Chao, Department of Occupational Safety and Health, Chung Shan Medical University, Taichung 402, Taiwan

Guest Editors

  • Pavel Rossner Jr., Laboratory of Genetic Ecotoxicology, Institute of Experimental Medicine, Academy of Sciences of the Czech Republic, Videnska 1083, 142 20 Prague, Czech Republic
  • Siamak Haghdoost, Centre for Radiation Protection Research, Department of Genetics, Microbiology and Toxicology, Stockholm University, 10691 Stockholm, Sweden
  • Hueiwang Anna Jeng, School of Community and Environmental Health, College of Health Sciences, Old Dominion University, Norfolk, VA 23529, USA
  • Chiung-Wen Hu, Department of Public Health, Chung Shan Medical University, Taichung 402, Taiwan