Oxidative Medicine and Cellular Longevity

Biological Efficacy of Medicinal Plant Extracts in Preventing Oxidative Damage


Publishing date
01 Jun 2018
Status
Published
Submission deadline
19 Jan 2018

1George Washington University, Washington, USA

2Ohio State University, Columbus, USA

3Babasaheb Ambedkar University, Lucknow, India


Biological Efficacy of Medicinal Plant Extracts in Preventing Oxidative Damage

Description

Reactive oxygen species (ROS), such as peroxides, superoxide, hydroxyl radicals, and singlet oxygen species and reactive nitrogen species (RNS), such as nitroxyl anion, nitrosonium cation, higher oxides of nitrogen, S-nitrosothiols, and dinitrosyl iron complexes, at physiological levels, are important signaling molecules maintaining cellular homeostasis. Redox imbalance is characteristic in the pathogenesis and pathophysiology of many diseases. Excessive ROS/RNS is either a cause or an important mediator of a number of pathologies. It results in oxidative damage to various biological macromolecules including DNA, lipids, and proteins, thereby altering several signaling pathways that ultimately promote cellular damage and death.

Many natural compounds and natural product mimics are potential antioxidants that protect against oxidative damage in chronic diseases such as neurodegenerative diseases, cardiovascular diseases, inflammatory conditions, and cancer. Understanding and validating the bioactivities of the natural compounds and the molecular mechanisms in preventing oxidative stress will provide solid scientific foundation to use the natural compounds for the prevention and treatment of oxidative stress-related diseases.

We invite researchers to contribute original research articles as well as review articles that will highlight the role of natural compounds or mimics that can ameliorate oxidative stress and reduce pathological complications associated with chronic diseases.

Potential topics include but are not limited to the following:

  • Dietary supplements/nutraceuticals mediated regulation of noncoding RNAs (miRNAs, lncRNAs, and circRNAs) for reducing oxidative and DNA damage
  • Novel antiageing compounds targeting oxidative stress
  • Medicinal extracts having potent immunomodulatory effects
  • Metabolomic characterization of naturally derived antioxidants
  • Efficacy of naturally derived antioxidants on tissue injury repair, diabetes, and cancer

Articles

  • Special Issue
  • - Volume 2018
  • - Article ID 7904349
  • - Editorial

Biological Efficacy of Medicinal Plant Extracts in Preventing Oxidative Damage

Jaideep Banerjee | Amitava Das | ... | Sudipta Saha
  • Special Issue
  • - Volume 2018
  • - Article ID 2314759
  • - Review Article

Ferulated Arabinoxylans and Their Gels: Functional Properties and Potential Application as Antioxidant and Anticancer Agent

Mayra Alejandra Mendez-Encinas | Elizabeth Carvajal-Millan | ... | Dora Edith Valencia-Rivera
  • Special Issue
  • - Volume 2018
  • - Article ID 7410389
  • - Research Article

Structural Characterization and Repair Mechanism of Gracilaria lemaneiformis Sulfated Polysaccharides of Different Molecular Weights on Damaged Renal Epithelial Cells

Da Guo | Kai Yu | ... | Jian-Ming Ouyang
  • Special Issue
  • - Volume 2018
  • - Article ID 7309073
  • - Review Article

Therapeutic Potential of Salviae Miltiorrhizae Radix et Rhizoma against Human Diseases Based on Activation of Nrf2-Mediated Antioxidant Defense System: Bioactive Constituents and Mechanism of Action

Guo-Hui Li | Yan-Ru Li | ... | Tao Shen
  • Special Issue
  • - Volume 2018
  • - Article ID 3246719
  • - Research Article

Antioxidant Activity and Genotoxic Assessment of Crabwood (Andiroba, Carapa guianensis Aublet) Seed Oils

Carlos F. Araujo-Lima | Andreia S. Fernandes | ... | Israel Felzenszwalb
  • Special Issue
  • - Volume 2018
  • - Article ID 1083596
  • - Research Article

The Critical Role of IL-10 in the Antineuroinflammatory and Antioxidative Effects of Rheum tanguticum on Activated Microglia

Jie Meng | Junjun Ni | ... | Hiroshi Nakanishi
  • Special Issue
  • - Volume 2018
  • - Article ID 1346958
  • - Research Article

Resveratrol Inhibits ROS-Promoted Activation and Glycolysis of Pancreatic Stellate Cells via Suppression of miR-21

Bin Yan | Liang Cheng | ... | Jiguang Ma
  • Special Issue
  • - Volume 2018
  • - Article ID 8487248
  • - Research Article

Evaluation of the Protective Effect of Olive Leaf Extract on Cisplatin-Induced Testicular Damage in Rats

Rafa S. Almeer | Ahmed E. Abdel Moneim
  • Special Issue
  • - Volume 2018
  • - Article ID 4039753
  • - Research Article

Antifibrogenic Influence of Mentha piperita L. Essential Oil against CCl4-Induced Liver Fibrosis in Rats

Hanan A. Ogaly | Nadia A. Eltablawy | Reham M. Abd-Elsalam
  • Special Issue
  • - Volume 2018
  • - Article ID 1821359
  • - Research Article

Recovery of Cardiac Remodeling and Dysmetabolism by Pancreatic Islet Injury Improvement in Diabetic Rats after Yacon Leaf Extract Treatment

Klinsmann Carolo dos Santos | Sarah Santiloni Cury | ... | Camila Renata Corrêa
Oxidative Medicine and Cellular Longevity
 Journal metrics
Acceptance rate48%
Submission to final decision56 days
Acceptance to publication37 days
CiteScore7.300
Impact Factor5.076
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