Lipid Peroxidation Products in Human Health and Disease
1Department of Biochemistry and Molecular Biology, The University of Texas Medical Branch, Galveston, TX 77555, USA
2Environmental Cardiology, University of Louisville, Louisville, KY 40202, USA
3Department of Diabetes and Metabolic Diseases Research, Beckman Research Institute, City of Hope National Medical Center, Duarte, CA, USA
Lipid Peroxidation Products in Human Health and Disease
Description
Oxidative stress and free radical reactions are important contributory factors to, or even direct progenitors of, tissue dysfunction and injury associated with aging and a number of pathological states such as carcinogenesis, diabetes, and atherosclerosis. Oxidative stress that causes lipid peroxidation in biological systems results in the formation of a wide variety of lipid hydroperoxides and aldehydes, which disseminate and augment the initial free radical injury. The unsaturated aldehydes produced by lipid peroxidation are potent electrophiles that alter vital cell signaling pathways and cause mitogenic, cytotoxic, and genotoxic reactions leading to various disease pathologies.
We invite authors to submit original research and review articles that explore aspects of lipid peroxidation products in human disease and health. Potential topics include, but are not limited to:
- Formation and determination of lipid peroxidation products
- Lipid peroxidation products in regulation of cell signaling
- Elucidating the role of lipid peroxidation in the development of human diseases
- Identification of lipid peroxidation products as biomarkers of human diseases
- Mechanism of action
- Lipid peroxidation in immune response
- Novel methods to identify the lipid peroxidation-derived products
Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/oximed/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/oximed/lpphhd/ according to the following timetable: