Oxidative Medicine and Cellular Longevity

Oxidative Stress in Disease and Aging: Mechanisms and Therapies


Status
Published

1Universidad Andrés Bello, Facultad de Ciencias Biológicas, Santiago, Chile

2Universidad Andrés Bello, Santiago, Chile

3Universität Heidelberg, Heidelberg, Germany

4Universidad Autónoma Madrid, Spain, Spain


Oxidative Stress in Disease and Aging: Mechanisms and Therapies

Description

The population affected by chronic disease and aging has been increasing in the last decades. Several and diverse causes produce these pathological states and a common mechanism involved in most of them is oxidative stress. Cellular oxidative stress is defined as an imbalance between formation of reactive oxygen species (ROS) and antioxidant defense mechanisms. Due to the broad and profound biological effects of ROS, in the last years numerous experimental and clinical studies have focused their attention on the participation of oxidative stress as a key regulator in chronic pathological status and aging.

We invite researchers and scientists to apply and contribute original research articles as well as review articles that reflect the progress to elucidate the mechanisms by which the balance between ROS and cellular antioxidant machinery may be altered during aging and chronic disease causing oxidative damage. We welcome all articles that describe new and important findings on the role of oxidative stress in disease or aging. It is expected the submission of manuscripts that allow expanding the knowledge and that describe new strategies to treat or prevent a pathological status in which oxidative stress might be involved.

Potential topics include, but are not limited to:

  • New mechanisms involved on the oxidative damage in aging and chronic diseases: role of ROS and antioxidant defense
  • Recent advances on cellular and molecular aspects of mechanism, therapy, or prevention of chronic diseases and age-related diseases in which oxidative stress is involved and potentially can be a target for interventions
  • Studies directed to find and develop new antioxidant drugs for prevention of chronic diseases and aging

Articles

  • Special Issue
  • - Volume 2016
  • - Article ID 8786564
  • - Editorial

Oxidative Stress in Disease and Aging: Mechanisms and Therapies

Claudio Cabello-Verrugio | Marta Ruiz-Ortega | ... | Felipe Simon
  • Special Issue
  • - Volume 2016
  • - Article ID 5194239
  • - Research Article

Superoxide Dismutase 1 Nanozyme for Treatment of Eye Inflammation

Olga A. Kost | Olga V. Beznos | ... | Alexander V. Kabanov
  • Special Issue
  • - Volume 2016
  • - Article ID 7095901
  • - Review Article

Critical Roles of Reactive Oxygen Species in Age-Related Impairment in Ischemia-Induced Neovascularization by Regulating Stem and Progenitor Cell Function

Yuen Ting Lam
  • Special Issue
  • - Volume 2016
  • - Article ID 3286365
  • - Research Article

Bioavailability Study of an Innovative Orobuccal Formulation of Glutathione

Daniela Buonocore | Matteo Grosini | ... | Fulvio Marzatico
  • Special Issue
  • - Volume 2016
  • - Article ID 5719291
  • - Research Article

Curcumin Supplementation Decreases Intestinal Adiposity Accumulation, Serum Cholesterol Alterations, and Oxidative Stress in Ovariectomized Rats

Maurilio da Silva Morrone | Carlos Eduardo Schnorr | ... | José Cláudio Fonseca Moreira
  • Special Issue
  • - Volume 2016
  • - Article ID 3571614
  • - Review Article

Sinapic Acid and Its Derivatives as Medicine in Oxidative Stress-Induced Diseases and Aging

Chunye Chen
  • Special Issue
  • - Volume 2016
  • - Article ID 6038798
  • - Research Article

Higher Urinary Levels of 8-Hydroxy-2′-deoxyguanosine Are Associated with a Worse RANKL/OPG Ratio in Postmenopausal Women with Osteopenia

Carlo Cervellati | Arianna Romani | ... | Gloria Bonaccorsi
  • Special Issue
  • - Volume 2016
  • - Article ID 9124676
  • - Research Article

Serum Superoxide Dismutase Is Associated with Vascular Structure and Function in Hypertensive and Diabetic Patients

Manuel A. Gómez-Marcos | Ana M. Blázquez-Medela | ... | Carlos Martínez-Salgado
  • Special Issue
  • - Volume 2015
  • - Article ID 416738
  • - Research Article

Glucose Oxidase Induces Cellular Senescence in Immortal Renal Cells through ILK by Downregulating Klotho Gene Expression

Nuria Troyano-Suárez | María del Nogal-Avila | ... | María Piedad Ruíz-Torres
  • Special Issue
  • - Volume 2015
  • - Article ID 964321
  • - Review Article

Key Roles of Glutamine Pathways in Reprogramming the Cancer Metabolism

Krzysztof Piotr Michalak | Agnieszka Maćkowska-Kędziora | ... | Piotr Woźniak
Oxidative Medicine and Cellular Longevity
 Journal metrics
Acceptance rate42%
Submission to final decision55 days
Acceptance to publication39 days
CiteScore7.300
Impact Factor5.076
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