Oxidative Medicine and Cellular Longevity

Oxidative Stress in Disease and Aging: Mechanisms and Therapies


Status
Published

1Universidad Andrés Bello, Facultad de Ciencias Biológicas, Santiago, Chile

2Universidad Andrés Bello, Santiago, Chile

3Universität Heidelberg, Heidelberg, Germany

4Universidad Autónoma Madrid, Spain, Spain


Oxidative Stress in Disease and Aging: Mechanisms and Therapies

Description

The population affected by chronic disease and aging has been increasing in the last decades. Several and diverse causes produce these pathological states and a common mechanism involved in most of them is oxidative stress. Cellular oxidative stress is defined as an imbalance between formation of reactive oxygen species (ROS) and antioxidant defense mechanisms. Due to the broad and profound biological effects of ROS, in the last years numerous experimental and clinical studies have focused their attention on the participation of oxidative stress as a key regulator in chronic pathological status and aging.

We invite researchers and scientists to apply and contribute original research articles as well as review articles that reflect the progress to elucidate the mechanisms by which the balance between ROS and cellular antioxidant machinery may be altered during aging and chronic disease causing oxidative damage. We welcome all articles that describe new and important findings on the role of oxidative stress in disease or aging. It is expected the submission of manuscripts that allow expanding the knowledge and that describe new strategies to treat or prevent a pathological status in which oxidative stress might be involved.

Potential topics include, but are not limited to:

  • New mechanisms involved on the oxidative damage in aging and chronic diseases: role of ROS and antioxidant defense
  • Recent advances on cellular and molecular aspects of mechanism, therapy, or prevention of chronic diseases and age-related diseases in which oxidative stress is involved and potentially can be a target for interventions
  • Studies directed to find and develop new antioxidant drugs for prevention of chronic diseases and aging

Articles

  • Special Issue
  • - Volume 2015
  • - Article ID 219569
  • - Research Article

An Increase of Plasma Advanced Oxidation Protein Products Levels Is Associated with Cardiovascular Risk in Incident Peritoneal Dialysis Patients: A Pilot Study

Elena Gonzalez | Maria-Auxiliadora Bajo | ... | Rafael Selgas
  • Special Issue
  • - Volume 2015
  • - Article ID 732596
  • - Review Article

Nrf2 Signaling and the Slowed Aging Phenotype: Evidence from Long-Lived Models

Danielle R. Bruns | Joshua C. Drake | ... | Karyn L. Hamilton
  • Special Issue
  • - Volume 2015
  • - Article ID 520872
  • - Research Article

pCramoll and rCramoll as New Preventive Agents against the Oxidative Dysfunction Induced by Hydrogen Peroxide

Luís Cláudio Nascimento da Silva | Neyla Maria Pereira Alves | ... | Regina Celia Bressan Queiroz de Figueiredo
  • Special Issue
  • - Volume 2015
  • - Article ID 964518
  • - Review Article

Mechanisms of Neuronal Protection against Excitotoxicity, Endoplasmic Reticulum Stress, and Mitochondrial Dysfunction in Stroke and Neurodegenerative Diseases

Howard Prentice | Jigar Pravinchandra Modi | Jang-Yen Wu
  • Special Issue
  • - Volume 2015
  • - Article ID 314560
  • - Review Article

Protective Mechanisms of Flavonoids in Parkinson’s Disease

Kasthuri Bai Magalingam | Ammu Kutty Radhakrishnan | Nagaraja Haleagrahara
  • Special Issue
  • - Volume 2015
  • - Article ID 619560
  • - Research Article

Dandelion Extracts Protect Human Skin Fibroblasts from UVB Damage and Cellular Senescence

Yafan Yang | Shuangshuang Li
  • Special Issue
  • - Volume 2015
  • - Article ID 682861
  • - Research Article

Regulation of MUTYH, a DNA Repair Enzyme, in Renal Proximal Tubular Epithelial Cells

Jianping Lu | Xinxiu Li | ... | Huimei Chen
  • Special Issue
  • - Volume 2015
  • - Article ID 362158
  • - Research Article

Nephroprotective Effects of Polydatin against Ischemia/Reperfusion Injury: A Role for the PI3K/Akt Signal Pathway

Hong-Bao Liu | Qiu-Hong Meng | ... | Xiao-Wei Liu
  • Special Issue
  • - Volume 2015
  • - Article ID 606981
  • - Research Article

Protective Effect of Edaravone in Primary Cerebellar Granule Neurons against Iodoacetic Acid-Induced Cell Injury

Xinhua Zhou | Longjun Zhu | ... | Yuqiang Wang
Oxidative Medicine and Cellular Longevity
 Journal metrics
Acceptance rate48%
Submission to final decision56 days
Acceptance to publication36 days
CiteScore7.300
Impact Factor5.076
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