Oxidative Medicine and Cellular Longevity

Yeast Stress, Aging, and Death


Publishing date
27 Sep 2013
Status
Published
Submission deadline
10 May 2013

1Department of Biology and Biotechnology “Charles Darwin”, Sapienza University of Rome, Piazzale Aldo Moro, Roma, Italy

2Istituto di Biomembrane e Bioenergetica, Consiglio Nazionale delle Ricerche, Via Amendola 165°, 70126 Bari, Italy

3Functional Biology and BioSCENTer, Institute of Botany and Microbiology, K.U. Leuven, Kasteelpark Arenberg 31, Box 2433, 3001 Heverlee, Belgium

4Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, Braga, Portugal; ICVS/3B's, PT Government Associate Laboratory, Braga/Guimaraes, University of Minho Campus Gualtar, 4710-057 Braga, Portugal


Yeast Stress, Aging, and Death

Description

Until about 15 years ago, programmed cell death, at that time mainly defined as apoptosis, was believed to be a feature occurring only in metazoans to ensure proper embryonic development, cell differentiation, and regulation of the immune response. However, the discovery that single-celled organisms, such as yeast, undergo programmed cell death as well challenged this idea. Meanwhile, several key regulators and cell death executers were shown to be highly conserved in yeast and other unicellular organisms, and it is now generally accepted that at least part of the molecular cell death machinery originated early in evolution.

Approximately 31% of the yeast genes have a mammalian homologue, and an additional 30% of yeast genes show domain similarity. This combined with the ease of manipulation of yeast and the elegance of yeast genetics has turned this lower eukaryote into an ideal system to study more complex phenomena that occur in metazoan cells, including stress responses, aging, and cell death as such or in the context of human diseases like cancer and neurodegenerative disorders.

We invite investigators to contribute original research articles as well as review articles that will stimulate the continuing efforts to understand the intimate links between the aforementioned processes. Potential topics include, but are not limited to:

  • Molecular factors and pathways contributing to cell death and/or aging
  • Mitochondrial function in stress response
  • Stress and death
  • Humanized yeast models
  • Aging and death networks, including approaches of systems biology
  • Prodeath and prolife cellular strategies
  • Oxidative damage and aging connections
  • Energy metabolism in stress, death and longevity

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/oximed/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/oximed/ysad/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2013
  • - Article ID 684395
  • - Editorial

Yeast Stress, Aging, and Death

Cristina Mazzoni | Sergio Giannattasio | ... | Paula Ludovico
  • Special Issue
  • - Volume 2013
  • - Article ID 320823
  • - Research Article

The Cell Wall Sensors Mtl1, Wsc1, and Mid2 Are Required for Stress-Induced Nuclear to Cytoplasmic Translocation of Cyclin C and Programmed Cell Death in Yeast

Chunyan Jin | Andrey V. Parshin | ... | Katrina F. Cooper
  • Special Issue
  • - Volume 2013
  • - Article ID 678473
  • - Research Article

Lack of HXK2 Induces Localization of Active Ras in Mitochondria and Triggers Apoptosis in the Yeast Saccharomyces cerevisiae

Loredana Amigoni | Enzo Martegani | Sonia Colombo
  • Special Issue
  • - Volume 2013
  • - Article ID 129645
  • - Research Article

A Novel Sit4 Phosphatase Complex Is Involved in the Response to Ceramide Stress in Yeast

Alexandra Woodacre | Museer A. Lone | ... | Raffael Schaffrath
  • Special Issue
  • - Volume 2013
  • - Article ID 612784
  • - Research Article

A Regulatory Role of NAD Redox Status on Flavin Cofactor Homeostasis in S. cerevisiae Mitochondria

Teresa Anna Giancaspero | Vittoria Locato | Maria Barile
  • Special Issue
  • - Volume 2013
  • - Article ID 704654
  • - Research Article

Potentiation of Antibiofilm Activity of Amphotericin B by Superoxide Dismutase Inhibition

Katrijn De Brucker | Anna Bink | ... | Karin Thevissen
  • Special Issue
  • - Volume 2013
  • - Article ID 161986
  • - Research Article

Ammonium-Dependent Shortening of CLS in Yeast Cells Starved for Essential Amino Acids Is Determined by the Specific Amino Acid Deprived, through Different Signaling Pathways

Júlia Santos | Cecília Leão | Maria João Sousa
  • Special Issue
  • - Volume 2013
  • - Article ID 493536
  • - Research Article

Mitochondrial DNA Instability in Cells Lacking Aconitase Correlates with Iron Citrate Toxicity

Muhammad A. Farooq | Tammy M. Pracheil | ... | Zhengchang Liu
  • Special Issue
  • - Volume 2013
  • - Article ID 802870
  • - Research Article

Ethanol and Acetate Acting as Carbon/Energy Sources Negatively Affect Yeast Chronological Aging

Ivan Orlandi | Rossella Ronzulli | ... | Marina Vai
  • Special Issue
  • - Volume 2013
  • - Article ID 437146
  • - Research Article

Saccharomyces cerevisiae Linker Histone—Hho1p Maintains Chromatin Loop Organization during Ageing

Katya Uzunova | Milena Georgieva | George Miloshev
Oxidative Medicine and Cellular Longevity
 Journal metrics
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Acceptance rate9%
Submission to final decision179 days
Acceptance to publication36 days
CiteScore10.100
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