Oxidative Medicine and Cellular Longevity

Strategies for Modulating Oxidative Stress under Diverse Physiological and Pathological Conditions


Publishing date
01 Sep 2018
Status
Published
Submission deadline
20 Apr 2018

1Nicolaus Copernicus University, Bydgoszcz, Poland

2The Franciszek Lukaszczyk Oncology Centre, Bydgoszcz, Poland

3University of Leuven, Leuven, Belgium

4Institut National de la Recherche Scientifique (INRS), Québec, Canada


Strategies for Modulating Oxidative Stress under Diverse Physiological and Pathological Conditions

Description

Oxidative stress occurs under numerous physiological and pathological conditions. The excess of reactive oxygen and nitrogen species, as well as the weakened antioxidant defense, is thought to play a significant role in the etiology of cancer, cardiovascular, neurodegenerative, and immune diseases, diabetes mellitus, obesity, aging, and others. Proantioxidant imbalance leads to the oxidative damage of several macromolecules, including DNA, proteins, and lipids that support the progress of many pathologies, including mutagen formation, cell dysfunction, and inflammatory state. Many efforts have been invested to understand the role of oxidative stress in the pathogenesis of chronic diseases. However, the effects of different strategies modifying oxidative stress on the development and prevention of these conditions are still not well understood and established. These strategies include not only supplementation with the substances that provide the antioxidant activity, but also different procedures, including physical activity, exercise, or therapeutic hypothermia and hypethermia. It is extremely important to undertand the mechanisms of operation of those strategies as to how they influence the antioxidant processes and in particular as to how they protect cells and organs against the deleterious action of the free radicals. Modern populations are affected by obesity, chronic diseases, and age related disorders such as dementia and Parkinson’s disease. That is why the expanding of the knowledge in the field of possible therapies and enhancing antioxidant defense seems to be crucial for the world healthcare.

We invite investigators to submit their original research, clinical studies, and review articles, describing the current findings on therapies modifying pro/antioxidant balance in health and in disease progression. We are particularly interested in articles that might contribute to better understanding of the biochemical and molecular mechanisms involved in the therapeutic strategies that may decrease oxidative stress and in consequence may influence the inflammatory state.

Potential topics include but are not limited to the following:

  • Potential topics include but are not limited to the following:
  • Identification of new therapies with working on antioxidant alteration processes in in animal and human cell models
  • Impact of physical activity, exercise, hypothermia, and hyperthermia on the oxidative stress in slim and obese subjects/experimental animals
  • Effects of antioxidant supplementation on physiological and pathological conditions in human
  • Influence of oxidative stress on immune system functions under health and disease condition

Articles

  • Special Issue
  • - Volume 2018
  • - Article ID 3987941
  • - Editorial

Strategies for Modulating Oxidative Stress under Diverse Physiological and Pathological Conditions

Karolina Szewczyk-Golec | Jolanta Czuczejko | ... | Joanna Lecka
  • Special Issue
  • - Volume 2018
  • - Article ID 9396089
  • - Research Article

Exogenous Hydrogen Sulfide Supplement Attenuates Isoproterenol-Induced Myocardial Hypertrophy in a Sirtuin 3-Dependent Manner

Jingyao Zhang | Jin Yu | ... | Guoliang Meng
  • Special Issue
  • - Volume 2018
  • - Article ID 9416432
  • - Research Article

Prophylactic Zinc and Therapeutic Selenium Administration Increases the Antioxidant Enzyme Activity in the Rat Temporoparietal Cortex and Improves Memory after a Transient Hypoxia-Ischemia

Constantino Tomas-Sanchez | Victor-Manuel Blanco-Alvarez | ... | Bertha Alicia Leon-Chavez
  • Special Issue
  • - Volume 2018
  • - Article ID 3420187
  • - Review Article

The Oxidative Stress and Mitochondrial Dysfunction during the Pathogenesis of Diabetic Retinopathy

Meng-Yu Wu | Giou-Teng Yiang | ... | Chia-Jung Li
  • Special Issue
  • - Volume 2018
  • - Article ID 6249536
  • - Research Article

The Role of Oxidative Stress, Selected Metals, and Parameters of the Immune System in Male Fertility

Michał Dobrakowski | Zbigniew Kaletka | ... | Aleksandra Kasperczyk
  • Special Issue
  • - Volume 2018
  • - Article ID 2056250
  • - Research Article

Anti-Inflammatory and Antioxidant Actions of Methyl Jasmonate Are Associated with Metabolic Modifications in the Liver of Arthritic Rats

Anacharis B. Sá-Nakanishi | Jamil Soni-Neto | ... | Jurandir F. Comar
  • Special Issue
  • - Volume 2018
  • - Article ID 4596746
  • - Research Article

Taurine Attenuates Calpain-2 Induction and a Series of Cell Damage via Suppression of NOX-Derived ROS in ARPE-19 Cells

Yuanyuan Zhang | Shu Ren | ... | Zhou Zhang
  • Special Issue
  • - Volume 2018
  • - Article ID 9658230
  • - Research Article

Renoprotective Effect of Platelet-Rich Plasma on Cisplatin-Induced Nephrotoxicity in Rats

Neveen Salem | Nawal Helmi | Naglaa Assaf
  • Special Issue
  • - Volume 2018
  • - Article ID 7671850
  • - Research Article

Analysis of Plasma MicroRNAs as Predictors and Biomarkers of Aging and Frailty in Humans

Iryna Rusanova | María E. Diaz-Casado | ... | Darío Acuña-Castroviejo
  • Special Issue
  • - Volume 2018
  • - Article ID 6857190
  • - Research Article

Resistance-Trained Individuals Are Less Susceptible to Oxidative Damage after Eccentric Exercise

Ypatios Spanidis | Dimitrios Stagos | ... | Demetrios Kouretas
Oxidative Medicine and Cellular Longevity
 Journal metrics
Acceptance rate42%
Submission to final decision55 days
Acceptance to publication39 days
CiteScore7.300
Impact Factor5.076
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