Oxidative Medicine and Cellular Longevity

The Role of Oxidative Stress in the Pathophysiology of Chronic Inflammatory Diseases


Publishing date
01 Nov 2019
Status
Closed
Submission deadline
21 Jun 2019

Lead Editor

1University of Porto, Porto, Portugal

2Federal University of Alagoas, Alagoas, Brazil

This issue is now closed for submissions.
More articles will be published in the near future.

The Role of Oxidative Stress in the Pathophysiology of Chronic Inflammatory Diseases

This issue is now closed for submissions.
More articles will be published in the near future.

Description

Chronic inflammatory diseases place a burden on the majority of health systems all around the world, essentially due to the lack of safe, effective, and affordable therapies. Diabetes, cardiovascular diseases, arthritis, allergies, and chronic obstructive pulmonary diseases are classified by the World Health Organization as specific chronic inflammation-mediated diseases. While multiple processes underlie these inflammation-mediated diseases, oxidative stress is undoubtedly involved in their pathogenesis as well as the development and establishment of a sustained inflammatory state.

Oxidative stress is caused by an overproduction of reactive oxygen species, resulting in deleterious effects such as oxidative damage of DNA, lipids, and proteins. It can also lead to the activation of various proinflammatory signaling pathways that result in the production of a series of cytokines and chemokines, eicosanoids, growth factors, cell cycle regulatory molecules, etc.

This special issue intends to gather original research and review articles that help to elucidate the role of oxidative stress in the pathophysiology of chronic inflammation-mediated diseases. We encourage the submission of in vitro (biochemical or cellular) and/or in vivo studies on inflammation; allergies; diabetes; arthritis and joint diseases; cardiovascular, renal, neurodegenerative, chronic obstructive pulmonary, and gastrointestinal diseases.

Potential topics include but are not limited to the following:

  • General role of oxidative stress in the inflammatory process
  • Cellular production of reactive species in inflammatory diseases
  • Detection of reactive species in inflammatory diseases
  • Expression/production/modulation of inflammatory mediators triggered by reactive prooxidant species
  • Strategies to prevent/treat oxidative stress-related inflammatory diseases
  • Findings on potential antioxidant/anti-inflammatory compounds, establishing the respective structure activity relationships (SAR)

Articles

  • Special Issue
  • - Volume 2020
  • - Article ID 3894309
  • - Research Article

Bacterial Endotoxin Induces Oxidative Stress and Reduces Milk Protein Expression and Hypoxia in the Mouse Mammary Gland

Alexander Jonathan Spitzer | Qing Tian | ... | Feng-Qi Zhao
  • Special Issue
  • - Volume 2019
  • - Article ID 8061901
  • - Research Article

The Oxidative Stress-Induced miR-200c Is Upregulated in Psoriasis and Correlates with Disease Severity and Determinants of Cardiovascular Risk

A. Magenta | M. D’Agostino | ... | G. Melillo
  • Special Issue
  • - Volume 2019
  • - Article ID 7536805
  • - Review Article

Oxidative Stress in Rheumatoid Arthritis: What the Future Might Hold regarding Novel Biomarkers and Add-On Therapies

Lucas José Sá da Fonseca | Valéria Nunes-Souza | ... | Luiza Antas Rabelo
  • Special Issue
  • - Volume 2019
  • - Article ID 8238727
  • - Review Article

Cross-Talk between Oxidative Stress and Inflammation in Preeclampsia

Marilene Brandão Tenório | Raphaela Costa Ferreira | ... | Marília Oliveira Fonseca Goulart
  • Special Issue
  • - Volume 2019
  • - Article ID 8982147
  • - Research Article

Lycorine Attenuates Autophagy in Osteoclasts via an Axis of mROS/TRPML1/TFEB to Reduce LPS-Induced Bone Loss

Hyun-Jung Park | Malihatosadat Gholam-Zadeh | ... | Hye-Seon Choi
  • Special Issue
  • - Volume 2019
  • - Article ID 6309465
  • - Research Article

Redox Balance Correlates with Nutritional Status among Patients with End-Stage Renal Disease Treated with Maintenance Hemodialysis

Małgorzata Maraj | Beata Kuśnierz-Cabala | ... | Marek Kuźniewski
  • Special Issue
  • - Volume 2019
  • - Article ID 9471697
  • - Research Article

Poor Glycaemic Control Is Associated with Increased Lipid Peroxidation and Glutathione Peroxidase Activity in Type 2 Diabetes Patients

Harshi Prasadini Gunawardena | Renuka Silva | ... | Prasad Katulanda
  • Special Issue
  • - Volume 2019
  • - Article ID 9187978
  • - Review Article

Antioxidants as Adjuvants in Periodontitis Treatment: A Systematic Review and Meta-Analysis

Micaele Maria Lopes Castro | Nathallia Neves Duarte | ... | Rafael Rodrigues Lima
  • Special Issue
  • - Volume 2019
  • - Article ID 6721531
  • - Research Article

T Cell-Derived IL-17A Induces Vascular Dysfunction via Perivascular Fibrosis Formation and Dysregulation of NO/cGMP Signaling

Rebecca Schüler | Panagiotis Efentakis | ... | Susanne Helena Karbach
  • Special Issue
  • - Volume 2019
  • - Article ID 5813985
  • - Research Article

Reactive Oxygen Species Are Involved in the Development of Gastric Cancer and Gastric Cancer-Related Depression through ABL1-Mediated Inflammation Signaling Pathway

Tianhe Huang | Fuling Zhou | ... | Yongchang Wei
Oxidative Medicine and Cellular Longevity
 Journal metrics
Acceptance rate42%
Submission to final decision56 days
Acceptance to publication37 days
CiteScore7.300
Impact Factor5.076
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