Oxidative Medicine and Cellular Longevity

Effects of Redox Disturbances on Motility, Contractility and Muscle Tissue Pathogenesis


Publishing date
01 May 2019
Status
Published
Submission deadline
28 Dec 2018

1Plymouth Marjon University, Plymouth, UK

2University of Padova, Padua, Italy

3Stellenbosch University, Stellenbosch, South Africa


Effects of Redox Disturbances on Motility, Contractility and Muscle Tissue Pathogenesis

Description

Whether in health or in disease, reactive oxygen and nitrogen species (ROS/RNS) affect muscle status and function. On the one hand, a challenge is to appreciate acute effects on contractility and/or bioenergetics within a realistic functional context, effectively linking in vitro observations to in vivo conditions. On the other hand, chronic effects on indices of clinical significance are more difficult to clarify given the interplay of redox status variations, with systemic inflammation and autophagy but also with lifestyle factors such as nutrition and physical activity.

The aim of the present special issue is to provide novel data regarding the role played by redox disturbances in the development of muscle dysfunction acutely and in the long term (e.g., toxicity, bed-rest, denervation), stressing the awareness of these concepts for the monitoring, interpretation, and management of disease effects on muscle. Thus, both original research articles and review articles, especially systematic or meta-analysis ones, are appropriate. Moreover, descriptive articles that provide novel information relevant to human noncommunicable diseases (affecting either smooth, skeletal, or cardiac muscles) based on human studies or animal models are also considered. In addition, articles addressing technological challenges and innovations on the use of redox biomarkers and/or proposing new methodologies aimed to measure ROS/RNS in vivo would be also welcome.

Potential topics include but are not limited to the following:

  • Direct (acute or chronic) effects of redox disturbances on contractility
  • The interplay between autophagy and oxidative stress signaling on muscle metabolism
  • Redox stress in models of chronic disease—progressive or end-stage
  • Challenges and advancements in monitoring redox disturbances in striated muscle
  • Efficacy of redox balance restoration strategies and therapeutic possibilities
  • Mechanisms underlying oxidative stress in muscle tissue pathogenesis including mitochondrial defects, calcium signaling alteration, or reduction of antioxidant defenses
  • Technical tools to measure redox homeostasis in muscle cells
  • Innovative clinical trials for so-far-untreatable muscle diseases

Articles

  • Special Issue
  • - Volume 2019
  • - Article ID 3272035
  • - Editorial

Effects of Redox Disturbances on Motility, Contractility and Muscle Tissue Pathogenesis

C. Karatzaferi | M. Sandri | ... | C. Smith
  • Special Issue
  • - Volume 2019
  • - Article ID 7064319
  • - Research Article

Abnormal Ribosome Biogenesis Partly Induced p53-Dependent Aortic Medial Smooth Muscle Cell Apoptosis and Oxidative Stress

Qi Wu | Junmou Hong | ... | Yongle Ruan
  • Special Issue
  • - Volume 2019
  • - Article ID 8219283
  • - Research Article

Evidence of Blood and Muscle Redox Status Imbalance in Experimentally Induced Renal Insufficiency in a Rabbit Model

Konstantina P. Poulianiti | Aggeliki Karioti | ... | Christina Karatzaferi
  • Special Issue
  • - Volume 2019
  • - Article ID 7623023
  • - Research Article

New Insights into the Hepcidin-Ferroportin Axis and Iron Homeostasis in iPSC-Derived Cardiomyocytes from Friedreich’s Ataxia Patient

Alessandra Bolotta | Provvidenza Maria Abruzzo | ... | Cinzia Zucchini
  • Special Issue
  • - Volume 2019
  • - Article ID 2484678
  • - Research Article

Redox Status and Muscle Pathology in Rheumatoid Arthritis: Insights from Various Rat Hindlimb Muscles

A. B. Oyenihi | T. Ollewagen | ... | C. Smith
  • Special Issue
  • - Volume 2019
  • - Article ID 9208949
  • - Research Article

Vagus Nerve Stimulation Attenuates Acute Skeletal Muscle Injury Induced by Ischemia-Reperfusion in Rats

Yifeng Zhang | Hewei Li | ... | Hong Jiang
  • Special Issue
  • - Volume 2019
  • - Article ID 4617801
  • - Review Article

Changes in Redox Signaling in the Skeletal Muscle with Aging

Péter Szentesi | László Csernoch | ... | Anikó Keller-Pintér
  • Special Issue
  • - Volume 2018
  • - Article ID 8927104
  • - Research Article

Upregulation of Heme Oxygenase-1 by Hemin Alleviates Sepsis-Induced Muscle Wasting in Mice

Xiongwei Yu | Wenjun Han | ... | Xiaoming Deng
  • Special Issue
  • - Volume 2018
  • - Article ID 6364821
  • - Research Article

Effects of Redox Disturbances on Intestinal Contractile Reactivity in Rats Fed with a Hypercaloric Diet

Iara L. L. de Souza | Elba dos S. Ferreira | ... | Bagnólia A. da Silva
  • Special Issue
  • - Volume 2018
  • - Article ID 8936251
  • - Research Article

Combination of Coenzyme Q10 Intake and Moderate Physical Activity Counteracts Mitochondrial Dysfunctions in a SAMP8 Mouse Model

C. Andreani | C. Bartolacci | ... | S. Silvestri
Oxidative Medicine and Cellular Longevity
 Journal metrics
Acceptance rate48%
Submission to final decision56 days
Acceptance to publication37 days
CiteScore7.300
Impact Factor5.076
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