Oxidative Medicine and Cellular Longevity

Plant-Derived Antioxidants in Disease Prevention 2018


Publishing date
01 Sep 2018
Status
Published
Submission deadline
27 Apr 2018

1AGH University of Science and Technology, Krakow, Poland

2Palacký University, Olomouc, Czech Republic

3Jagiellonian University, Krakow, Poland


Plant-Derived Antioxidants in Disease Prevention 2018

Description

Oxidative stress is generated by an imbalance between reactive oxygen species (ROS) and antioxidants. An excess of ROS leads to the degradation of lipids, proteins, and DNA and thus may lead to oxidative damage to cells and, in consequence, to the overexpression of oncogenes, mutagen formation, the induction of atherogenic activity, or inflammation. Oxidative stress is thought to play a major role in the pathogenesis of cardiovascular diseases, neurodegeneration, cancer, immune disorders, diabetes, aging, and others. Plants, especially dietary fruits and vegetables, are a rich source of antioxidants. It is postulated that antioxidants produce health benefits through the direct reduction of oxidative stress. In the body, the antioxidant network works in concert through several different mechanisms: ROS scavenging, lipid peroxidation, and the inhibition or chelation of metals. However, our understanding of the specific role and mechanisms of the action of certain antioxidants is still in infancy. Many in vitro and in vivo studies indicate that a single antioxidant (i.e., β-carotene and vitamin C or vitamin E) or diets rich in plant food provide protection against a set of diseases. However, several clinical trials on antioxidant action have produced contrasting results, with some showing a positive effect and others showing no evident results or even an increase in mortality.

We invite authors to submit original research as well as review articles that seek to understand the strategies and mechanisms of plant-derived antioxidants action in disease prevention. We are interested in articles that explore aspects of natural antioxidant action in humans and also in animal models. We are particularly interested in articles describing novel antioxidants, original approaches, and clinical studies on plant antioxidant involvement in disease prevention and treatment.

Potential topics include but are not limited to the following:

  • Recent developments in plant-derived antioxidant research
  • Isolation and testing of novel and effective natural antioxidants
  • Role of plant-derived antioxidants in disease prevention
  • Identification of new, possible therapeutic mechanisms of antioxidant action
  • Latest strategies for clinical evaluation and measuring
  • Meta-analysis of randomized clinical trials to assess the beneficial or harmful effects of antioxidant supplements for disease prevention

Articles

  • Special Issue
  • - Volume 2018
  • - Article ID 2068370
  • - Editorial

Plant-Derived Antioxidants in Disease Prevention 2018

Renata Szymanska | Pavel Pospíšil | Jerzy Kruk
  • Special Issue
  • - Volume 2018
  • - Article ID 6594101
  • - Research Article

Extracts from the Mediterranean Food Plants Carthamus lanatus, Cichorium intybus, and Cichorium spinosum Enhanced GSH Levels and Increased Nrf2 Expression in Human Endothelial Cells

Dimitrios Stagos | Dimitrios Balabanos | ... | Demetrios Kouretas
  • Special Issue
  • - Volume 2018
  • - Article ID 9101740
  • - Research Article

Hydroxysafflor Yellow A Shows Protection against PPARγ Inactivation in Nitrosative Neurons

Li Sun | Yan-Wei Xu | ... | Yan Cheng
  • Special Issue
  • - Volume 2018
  • - Article ID 1630751
  • - Research Article

Lycium europaeum Extract: A New Potential Antioxidant Source against Cisplatin-Induced Liver and Kidney Injuries in Mice

Ilhem Rjeibi | Anouar Feriani | ... | Najla Hfaiedh
  • Special Issue
  • - Volume 2018
  • - Article ID 3685391
  • - Research Article

Gastrodin Protects Cardiomyocytes from Anoxia/Reoxygenation Injury by 14-3-3η

Meifang Zhu | Wei Deng | ... | Bo Yi
  • Special Issue
  • - Volume 2018
  • - Article ID 4069167
  • - Research Article

Chlorophyll-Mediated Changes in the Redox Status of Pancreatic Cancer Cells Are Associated with Its Anticancer Effects

Kateřina Vaňková | Ivana Marková | ... | Libor Vítek
  • Special Issue
  • - Volume 2018
  • - Article ID 2935051
  • - Research Article

Guazuma ulmifolia Lam. Decreases Oxidative Stress in Blood Cells and Prevents Doxorubicin-Induced Cardiotoxicity

Jéssica Maurino dos Santos | Tamaeh Monteiro Alfredo | ... | Kely de Picoli Souza
  • Special Issue
  • - Volume 2018
  • - Article ID 6241017
  • - Review Article

Rutin as a Potent Antioxidant: Implications for Neurodegenerative Disorders

Adaze Bijou Enogieru | William Haylett | ... | Okobi Eko Ekpo
  • Special Issue
  • - Volume 2018
  • - Article ID 4327901
  • - Research Article

Aucubin Protects against Myocardial Infarction-Induced Cardiac Remodeling via nNOS/NO-Regulated Oxidative Stress

Zheng Yang | Qing-Qing Wu | ... | Qi-Zhu Tang
  • Special Issue
  • - Volume 2018
  • - Article ID 8275256
  • - Review Article

The Role of Saikosaponins in Therapeutic Strategies for Age-Related Diseases

Byeong Mo Kim
Oxidative Medicine and Cellular Longevity
 Journal metrics
Acceptance rate48%
Submission to final decision56 days
Acceptance to publication37 days
CiteScore7.300
Impact Factor5.076
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