Oxidative Medicine and Cellular Longevity

The Janus of Oxidative Stress Signaling in Different Pathophysiological Conditions


Publishing date
28 Jun 2013
Status
Published
Submission deadline
08 Feb 2013

1Graduate Centre of Toxicology, Lexington, KY 40536, USA

2Cardiovascular Research Center, University of Kentucky, Lexington, KY 40536, USA

3Department of Pathology, University of Alabama at Birmingham, AL 35233, USA

4Centocor, Inc., Malvern, PA 19355, USA

5National Primate Research Center, University of Wisconsin-Madison, Madison, WI 53705, USA


The Janus of Oxidative Stress Signaling in Different Pathophysiological Conditions

Description

While reactive oxygen species (ROS)/reactive nitrogen species (RNS) are important for normal cellular activities, deviant production of ROS, or diminished capacity to scavenge excessive ROS, leads to an imbalance in the redox environment of the cell. Given the dual role of ROS in normal cell functioning and maintaining homeostasis by clearance of excess ROS, indepth analysis of oxidative stress, under both normal and disease conditions will result in better understanding of disease-specific altered pathways. Additionally, mechanistic studies targeted towards deciphering regulation of cell-specific ROS in global gene expression, can illuminate the contribution of mitochondria and other cell organelles in the development of disease and may lead to the advancement of new and novel therapeutic modalities that exploit oxidative stress in treating many diseases.

We invite investigators to contribute original research as well as review articles that will stimulate the continuing efforts to understand the Janus of oxidative stress signaling. We are interested in articles which focus on altered cellular ROS or oxidative stress signaling in various pathophysiological conditions. Potential topics include, but are not limited to (oxidative stress could be related to reactive oxygen species/reactive nitrogen species):

  • Oxidative stress/reactive oxygen species signaling
  • Oxidative stress and mitochondrial signaling
  • Endoplasmic reticulum stress
  • Mitochondrial retrograde signaling
  • Oxidative and reductive stress
  • Therapeutic effects of controlling the ROS
  • Pattern recognition receptors and ROS signaling
  • ROS/oxidative stress in various pathophysiological conditions (diabetes, colitis, osteoporosis, aging, Alzheimer's disease, and toxicologically related diseases)

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/oximed/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/oximed/joss/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2013
  • - Article ID 708796
  • - Editorial

The Janus of Oxidative Stress Signaling in Different Pathophysiological Conditions

Sumitra Miriyala | Manikandan Panchatcharam | ... | Anantharaman Muthuswamy
  • Special Issue
  • - Volume 2013
  • - Article ID 853210
  • - Research Article

A Novel Tetrapeptide Derivative Exhibits In Vitro Inhibition of Neutrophil-Derived Reactive Oxygen Species and Lysosomal Enzymes Release

Sumitra Miriyala | Manikandan Panchatcharam | ... | Rengarajulu Puvanakrishnan
  • Special Issue
  • - Volume 2013
  • - Article ID 351613
  • - Review Article

Mitochondrial Signaling: Forwards, Backwards, and In Between

Sean P. Whelan | Brian S. Zuckerbraun
  • Special Issue
  • - Volume 2013
  • - Article ID 452546
  • - Research Article

Oxidative Stress and Free-Radical Oxidation in BCG Granulomatosis Development

Elena Menshchikova | Nikolay Zenkov | ... | Vyacheslav Shkurupiy
  • Special Issue
  • - Volume 2013
  • - Article ID 862423
  • - Review Article

Reactive Oxygen Species and the Cardiovascular System

Yannick J. H. J. Taverne | Ad J. J. C. Bogers | ... | Daphne Merkus
  • Special Issue
  • - Volume 2013
  • - Article ID 186795
  • - Research Article

Adaptive Redox Response of Mesenchymal Stromal Cells to Stimulation with Lipopolysaccharide Inflammagen: Mechanisms of Remodeling of Tissue Barriers in Sepsis

Nikolai V. Gorbunov | Bradley R. Garrison | ... | Juliann G. Kiang
  • Special Issue
  • - Volume 2013
  • - Article ID 297357
  • - Review Article

Nitric Oxide Donors as Neuroprotective Agents after an Ischemic Stroke-Related Inflammatory Reaction

Marisol Godínez-Rubí | Argelia E. Rojas-Mayorquín | Daniel Ortuño-Sahagún
  • Special Issue
  • - Volume 2013
  • - Article ID 649809
  • - Research Article

Enhanced Prostacyclin Synthesis by Adenoviral Gene Transfer Reduced Glial Activation and Ameliorated Dopaminergic Dysfunction in Hemiparkinsonian Rats

May-Jywan Tsai | Ching-Feng Weng | ... | Henrich Cheng
  • Special Issue
  • - Volume 2013
  • - Article ID 962984
  • - Review Article

Link between Cancer and Alzheimer Disease via Oxidative Stress Induced by Nitric Oxide-Dependent Mitochondrial DNA Overproliferation and Deletion

Gjumrakch Aliev | Mark E. Obrenovich | ... | Mohammad Amjad Kamal
  • Special Issue
  • - Volume 2013
  • - Article ID 781050
  • - Review Article

Increased Nitroxidative Stress Promotes Mitochondrial Dysfunction in Alcoholic and Nonalcoholic Fatty Liver Disease

Byoung-Joon Song | Mohamed A. Abdelmegeed | ... | Kwan-Hoon Moon
Oxidative Medicine and Cellular Longevity
 Journal metrics
Acceptance rate48%
Submission to final decision56 days
Acceptance to publication37 days
CiteScore7.300
Impact Factor5.076
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