Oxidative Medicine and Cellular Longevity

Oxidative Stress-Mediated Reperfusion Injury 2014


Status
Published

Lead Editor

1The University of Hong Kong, Pokfulam, Hong Kong

2Wright State University Boonshoft School of Medicine, Dayton, USA

3Capital University of Medical Sciences, Beijing, China

4University of Calgary, Calgary, Canada

5Sun Yat-sen University, Guangzhou, China


Oxidative Stress-Mediated Reperfusion Injury 2014

Description

Oxidative stress plays an important role in the pathogenesis of ischemia reperfusion injury. The mechanisms underlying ischaemia/reperfusion injury have been extensively studied using healthy tissues, yet less attention has been devoted to defining how the different risk factors such as diabetes and aging (situations that are associated with increased oxidative stress) may influence the degree of organ or cellular injury under pathological conditions like ischemia/reperfusion. While rapid production of large amount of reactive oxygen species (ROS), called oxidative burst, causes oxidative damage which contributes significantly to ischemia reperfusion injury, moderate elevation of ROS production induced by therapeutic interventions like ischemic or pharmacologic preconditioning may trigger cellular protective signaling pathways, leading to the attenuation of ischemia reperfusion injury.

We invite investigators to contribute original research articles as well as review articles that will stimulate the continuing efforts to understand the molecular mechanism underlying ischemia/reperfusion injury under normal and diseased conditions to develop strategies to treat these pathological conditions.

Potential topics include, but are not limited to:

  • Role of reactive oxygen species (ROS) in organ (heart, lung, brain, liver, kidney, and/or intestine) ischemia reperfusion injury under normal and diseased (e.g., diabetes and hypertension) conditions
  • Cellular protective signaling pathways that ROS may trigger that contribute to cellular repairing during ischemia reperfusion injury and the potential interplay between these pathways
  • Cardioprotection in aged and/or functionally impaired hearts
  • Role of reperfusion-induced oxidative stress and inflammation in mediating remote organ injury
  • Recent advances in preventing ischemia-reperfusion injury

Articles

  • Special Issue
  • - Volume 2015
  • - Article ID 364020
  • - Research Article

Mechanical Ventilation Induces an Inflammatory Response in Preinjured Lungs in Late Phase of Sepsis

Wei Xuan | Quanjun Zhou | ... | Qingping Wu
  • Special Issue
  • - Volume 2015
  • - Article ID 843721
  • - Research Article

Ginsenoside Rb1 Treatment Attenuates Pulmonary Inflammatory Cytokine Release and Tissue Injury following Intestinal Ischemia Reperfusion Injury in Mice

Ying Jiang | Zhen Zhou | ... | Zhong-yuan Xia
  • Special Issue
  • - Volume 2015
  • - Article ID 486148
  • - Research Article

Glutathione Supplementation Attenuates Oxidative Stress and Improves Vascular Hyporesponsiveness in Experimental Obstructive Jaundice

Jiaying Chen | Feixiang Wu | ... | Weifeng Yu
  • Special Issue
  • - Volume 2015
  • - Article ID 590987
  • - Review Article

Oxidative Stress and Lung Ischemia-Reperfusion Injury

Renata Salatti Ferrari | Cristiano Feijó Andrade
  • Special Issue
  • - Volume 2015
  • - Article ID 125106
  • - Research Article

High-Dose Polymerized Hemoglobin Fails to Alleviate Cardiac Ischemia/Reperfusion Injury due to Induction of Oxidative Damage in Coronary Artery

Qian Yang | Wei Wu | ... | Tao Li
  • Special Issue
  • - Volume 2015
  • - Article ID 352723
  • - Review Article

The Ambiguous Relationship of Oxidative Stress, Tau Hyperphosphorylation, and Autophagy Dysfunction in Alzheimer’s Disease

Zhenzhen Liu | Tao Li | ... | Jianshe Wei
  • Special Issue
  • - Volume 2015
  • - Article ID 756576
  • - Research Article

Genome-Wide Expression Profiling of Anoxia/Reoxygenation in Rat Cardiomyocytes Uncovers the Role of Mito in Energy Homeostasis

Song Cao | Yun Liu | ... | Tian Yu
  • Special Issue
  • - Volume 2015
  • - Article ID 186736
  • - Clinical Study

Dexmedetomidine Analgesia Effects in Patients Undergoing Dental Implant Surgery and Its Impact on Postoperative Inflammatory and Oxidative Stress

Sisi Li | Yang Yang | ... | Chi Wai Cheung
  • Special Issue
  • - Volume 2014
  • - Article ID 134862
  • - Research Article

Cardioprotection against Ischemia/Reperfusion by Licochalcone B in Isolated Rat Hearts

Jichun Han | Dong Wang | ... | Qiusheng Zheng
Oxidative Medicine and Cellular Longevity
 Journal metrics
Acceptance rate48%
Submission to final decision56 days
Acceptance to publication37 days
CiteScore7.300
Impact Factor5.076
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