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Prostate Cancer
Volume 2011, Article ID 234519, 9 pages
Clinical Study

Racial/Ethnic Patterns in Prostate Cancer Outcomes in an Active Surveillance Cohort

1Center for Prostate Disease Research, Department of Defense, Rockville, MD 20852, USA
2Walter Reed Army Medical Center, Washington, DC, USA
3Virginia Mason Medical Center, Seattle, WA, USA
4Naval Medical Center San Diego, San Diego, CA, USA
5Madigan Army Medical Center, Tacoma, WA, USA

Received 15 January 2011; Revised 14 April 2011; Accepted 27 April 2011

Academic Editor: I. J. Powell

Copyright © 2011 Jennifer Cullen et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Introduction. Concern regarding overtreatment of prostate cancer (CaP) is leading to increased attention on active surveillance (AS). This study examined CaP survivors on AS and compared secondary treatment patterns and overall survival by race/ethnicity. Methods. The study population consisted of CaP patients self-classified as black or white followed on AS in the Center for Prostate Disease Research (CPDR) multicenter national database between 1989 and 2008. Secondary treatment included radical prostatectomy (RP), external beam radiation therapy or brachytherapy (EBRT-Br), and hormone therapy (HT). Secondary treatment patterns and overall survival were compared by race/ethnicity. Results. Among 886 eligible patients, 21% were black. Despite racial differences in risk characteristics and secondary treatment patterns, overall survival was comparable across race. RP following AS was associated with the longest overall survival. Conclusion. Racial disparity in overall survival was not observed in this military health care beneficiary cohort with an equal access to health care.