Clinical Study
A Retrospective Study on Pathologic Features and Racial Disparities in Prostate Cancer
Table 2
Differences in features at time of diagnosis of Pca between African Americans and Caucasians.
| | Features | African American (n) | Caucasian (n) | P value |
| | Prostate cancer detection rate (%) | 49.2 (620) | 40.8 (416) | <0.0001a | | Age (year, mean±SD) | (620) | (414) | 0.0081 | | Gleason score (mean±SD) | (611) | (410) | <0.0001 | | Serum PSA (ng/mL, median) | 11.1 (404) | 7 (213) | <0.0001 | | Diagnosed by biopsy (%) | 88.9 (551) | 79.6 (331) | <0.000b | | First biopsy (%) | 82.1 (509) | 70.5 (293) | <0.0001c | | Repeated biopsies (%) | 6.8 (42) | 9.1 (38) | >0.05 | | Diagnosed by TURP* (%) | 6.5 (40) | 9.6 (40) | 0.074d | | Diagnosed by prostatectomy (%) | 4.7 (29) | 10.8 (45) | <0.0001e |
|
|
*TURP: Transurethral resection of prostate; a: OR = 1.4, 95% CI: 1.19–1.66; b: OR = 2.1, 95% CI: 1.45–2.89; c: OR = 1.93, 95% CI: 1.44–2.58; d: OR = 0.65, 95% CI: 0.41–1.02: e: OR = 0.41, 95% CI: 0.25–0.65.
|
