Prostate Cancer Severity Associations with Neighborhood Deprivation

Table 3

Unstratified analysis—associations of neighborhood SES characteristics with indicators of prostate cancer severity (GEE) adjusted for age, race, and diagnosis year.

Effect	Tumor aggressiveness		High stage		High Gleason
	OR (CI)	P value	OR (CI)	P-value	OR (CI)	P-value
African American race/ethnicity	1.31 (1.16, 1.47)	<.001	1.27 (1.17, 1.39)	<.001	1.37 (1.27, 1.47)	<.001
≥ Median % neighborhood poverty	0.99 (0.87, 1.12)	0.853	0.93 (0.84, 1.02)	0.126	1.09 (1.01, 1.17)	0.028
African American race/ethnicity	1.32 (1.15, 1.50)	<.001	1.32 (1.20, 1.46)	<.001	1.31 (1.21, 1.42)	<.001
≥ Median % household income <$30,000	1.05 (0.93, 1.19)	0.446	1.00 (0.91, 1.10)	0.998	1.10 (1.02, 1.19)	0.014
African American race/ethnicity	1.28 (1.12, 1.46)	<.001	1.27 (1.15, 1.41)	<.001	1.31 (1.20, 1.42)	<.001
< Median % high school education	1.12 (1.00, 1.27)	0.054	1.01 (0.92, 1.11)	0.802	1.10 (1.02, 1.19)	0.010
African American race/ethnicity	1.24 (1.09, 1.41)	<.001	1.27 (1.15, 1.39)	<.001	1.31 (1.21, 1.42)	<.001
≥ Median % female head of household with dependent child(ren)	1.02 (0.90, 1.16)	0.727	0.94 (0.85, 1.04)	0.217	1.09 (1.01, 1.17)	0.030
African American race/ethnicity	1.29 (1.13, 1.48)	<.001	1.31 (1.19, 1.45)	<.001	1.31 (1.21, 1.42)	<.001
≥ Median % households with no car	1.01 (0.90, 1.14)	0.845	0.93 (0.85, 1.03)	0.161	1.13 (1.05, 1.22)	0.001
African American race/ethnicity	1.30 (1.14, 1.48)	<.001	1.32 (1.19, 1.45)	<.001	1.28 (1.18, 1.40)	<.001
≥ Median % public assistance	0.97 (0.85, 1.09)	0.576	0.89 (0.81, 0.99)	0.026	1.08 (1.00, 1.16)	0.063
African American race/ethnicity	1.33 (1.17, 1.52)	<.001	1.34 (1.22, 1.49)	<.001	1.32 (1.21, 1.43)	<.001
Deprivation quartile		0.064		0.245		<.001
Deprivation quartile 2 versus 1	1.07 (0.92, 1.24)	0.390	0.99 (0.88, 1.12)	0.882	1.06 (0.98, 1.16)	0.165
Deprivation quartile 3 versus 1	0.94 (0.80, 1.11)	0.470	0.89 (0.78, 1.02)	0.083	1.03 (0.93, 1.15)	0.543
Deprivation quartile 4 versus 1	1.19 (0.99, 1.43)	0.068	0.99 (0.86, 1.14)	0.927	1.36 (1.22, 1.51)	<.001
African American race/ethnicity	1.20 (1.03, 1.39)	0.020	1.27 (1.14, 1.42)	<.001	1.16 (1.06, 1.26)	<.001

^∗<.05, ^∗∗<.01, ^∗∗∗<.001.