Hypofractionated Proton Boost Combined with External Beam Radiotherapy for Treatment of Localized Prostate Cancer

Table 2

Cox regression model—PSA relapse.

	Univariate analysis			Multivariate analysis
	HR	(95% CI)	𝑃	HR	(95% CI)	𝑃
Age at diagnosis, continuous	0.99	(0.93–1.06)	0.741	0.99	(0.93–1.05)	0.726
T-stage
T1	1.00	(ref.)	—	1.00	(ref.)	—
T2	4.25	(0.90–20.02)	0.067	3.63	(0.76–17.36)	0.106
T3	16.70	(3.92–71.11)	<0.001	9.67	(2.13–43.89)	0.003
T4	45.91	(6.41–329.02)	<0.001	14.80	(1.82–120.24)	0.012
Gleason score, continuous	2.05	(1.53–2.75)	<0.001	1.43	(1.02–2.00)	0.038
log-PSA, continuous	2.27	(1.54–3.34)	<0.001	1.40	(0.92–2.14)	0.115
Rectal rod
No	1.00	(ref.)	—	1.00	(ref.)	—
Yes	1.99	(0.93–4.25)	0.074	1.21	(0.53–2.76)	0.653