Hypofractionated Proton Boost Combined with External Beam Radiotherapy for Treatment of Localized Prostate Cancer

Table 3

Cox regression model—distant metastases.

	Univariate analysis			Multivariate analysis
	HR	(95% CI)	𝑃	HR	(95% CI)	𝑃
Age at diagnosis, continuous	1.00	(0.93–1.08)	0.966	0.99	(0.92–1.06)	0.713
T-stage
T1	1.00	(ref.)	—	1.00	(ref.)	—
T2	2.08	(0.38–11.38)	0.397	1.94	(0.35–10.84)	0.451
T3	11.92	(2.75–51.62)	<0.001	7.79	(1.65–36.81)	0.010
T4	19.91	(1.79–221.62)	0.015	8.64	(0.67–111.96)	0.099
Gleason score, continuous	2.01	(1.44–2.80)	<0.001	1.48	(1.02–2.13)	0.037
log-PSA, continuous	1.76	(1.08–2.86)	0.024	1.08	(0.64–1.83)	0.776