Research Article

Obesity and the Odds of Weight Gain following Androgen Deprivation Therapy for Prostate Cancer

Table 3

Distribution of weight gain 6 months following randomization, stratified by treatment received and body mass index.

RT only ( )RT + ADT ( )
Weight change 6 months following randomization
<10 lbs ( ) ≥10 lbs ( )<10 lbs ( )≥10 lbs ( )

BMI (range in kg/m2)(Range −13 to +9; median −1 lb)(Range 10 to 13; median +11.5 lbs)(Range −11 to +8; median +1 lb)(Range 10 to 17 lbs; median +11.25 lbs)
 Normal (18.5–24.9)17 (20%)1 (50%)22 (29%)2 (20%)
 Overweight (25.0–29.9)43 (52%)1 (50%)37 (49%)1 (10%)
 Obese (≥30.0)23 (28%)0 (0%)17 (22%)7 (70%)
Fisher’s exact test value = 0.45Fisher’s exact test value = 0.006

RT indicates radiotherapy; ADT: androgen deprivation therapy; BMI: body mass index.