Research Article

Assessment of the Performance of Magnetic Resonance Imaging/Ultrasound Fusion Guided Prostate Biopsy against a Combined Targeted Plus Systematic Biopsy Approach Using 24-Core Transperineal Template Saturation Mapping Prostate Biopsy

Table 6

Missed cancers (cancers detected on TTMB but missed on MRI targeted biopsy: significant upgrades only).

TTMB dataMRI/US fusion targeted biopsy data
GS (% Gleason 4)Location of cancerGSLocation of ROIMRI ROI location correlates to TTMBROI size (mm)PI-RAD score

3 + 4 (15%)L ant0L base postNo72
3 + 4 (5%)R mid post0L post apexNo43
3 + 4 (10%)L post apex0Midline postNo113
3 + 4 (10%)R base PL + R ant0R mid apexNo53
3 + 4 (10%)R base PL3 + 3R base peripheral zonePartial123
3 + 4 (2%)L ant apex, R mid PL, L mid PL3 + 3L post apexPartial94
3 + 4 (5%)R base PL0L baseNo25

MRI/US-TBx = MRI/transrectal ultrasound fusion targeted biopsy, TTMB = transperineal template guided mapping biopsy, ROI = region of interest, L = left, R = right, ant = anterior, post = posterior, and PL = posterolateral.