Analysis of Argonaute Complex Bound mRNAs in DU145 Prostate Carcinoma Cells Reveals New miRNA Target Genes

Figure 1

Quantification of mRNA expression in primary normal prostate (PNF-08) cells and the DU145 and LNCaP PCa cell lines. The expression of ten mRNAs that were assumed to be elevated or reduced according to their presence or absence in the Ago complex was assessed by qRT-PCR. YWHAE, TRFC, CORO1C, and PRDX3 were predicted to be elevated while, NLK, RAB1B, DEDD, CUL5, EI24, and S100A16 were predicted to be reduced in PCa cells as compared to PNF-08 cells.