Research Article

Achieving PSA < 0.2 ng/ml before Radiation Therapy Is a Strong Predictor of Treatment Success in Patients with High-Risk Locally Advanced Prostate Cancer

Table 1

Patient and treatment characteristics, compared between patients with a pre-RT PSA <0.2 ng/ml and ≥0.2 ng/ml.

VariablesAllPre-RT PSA < 0.2Pre-RT PSA ≥ 0.2
()()()

Age [y.o.], median (range)71 (57–83)71 (57–83)71 (58–82)
Initial PSA [ng/ml], median (range)24.7 (1.9–282.5)20.3 (1.9–268)31.0 (5.33–282.5)

Clinical T stage, (%)
T136 (17.7)18 (17.1)18 (8.2)
T238 (18.6)17 (16.2)21 (21.2)
T3123 (60.3)68 (64.8)55 (55.6)
T47 (3.4)2 (1.9)5 (5.0)
Gleason score, (%)
7 or less73 (35.8)34 (32.4)39 (39.3)
8 or higher131 (64.2)71 (67.6)60 (60.7)
No. NCCN high risk factor, (%)
185 (41.7)45 (42.9)40 (40.4)
2 or 3119 (58.3)60 (57.1)59 (59.6)
LH-RH agonist + bicalutamide, (%)
Yes142 (69.6)95 (90.5)47 (47.5)
No62 (30.4)10 (95)52 (52.5)
Follow-up period [mo], median (IQR)113 (95–128)
Neoadjuvant HT [mo], median (IQR)7 (6–10)
Total HT [mo], median (IQR)27 (14–38)
PSA before RT [ng/ml], median (range)0.20 (0.01–22.1)