Prostate Cancer / 2020 / Article / Fig 4

Research Article

Interleukin-10 Induces Expression of Neuroendocrine Markers and PDL1 in Prostate Cancer Cells

Figure 4

Slight upregulation of EP4 in IL10, IL6, and ENZ treated LNCaP cells. (a) LNCaP, (b) 16DCRPC, (c) 46DENZR resistant cells were stimulated with 100 ng/mL IL10, IL6, or ENZ for 7 days prior to lysate collection. Expression levels of EP4 were determined by immunoblotting of cell lysates. Data plotted represents EP4 band intensities normalized to GAPDH protein levels. Experiments were repeated 3 times. The statistical significance for the difference between untreated and different treatment was determined by one-way ANOVA with Tukey’s corrections. , , and ; ns = not significant.

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