Interleukin-10 Induces Expression of Neuroendocrine Markers and PDL1 in Prostate Cancer Cells
Slight upregulation of EP4 in IL10, IL6, and ENZ treated LNCaP cells. (a) LNCaP, (b) 16DCRPC, (c) 46DENZR resistant cells were stimulated with 100 ng/mL IL10, IL6, or ENZ for 7 days prior to lysate collection. Expression levels of EP4 were determined by immunoblotting of cell lysates. Data plotted represents EP4 band intensities normalized to GAPDH protein levels. Experiments were repeated 3 times. The statistical significance for the difference between untreated and different treatment was determined by one-way ANOVA with Tukey’s corrections. ,, and ; ns = not significant.
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