Management of Patients with Nonmetastatic Castration-Resistant Prostate Cancer: Recommendations of a Multidisciplinary Panel of Experts from South America
Box 3
Recommendations regarding adverse events in the treatment of patients with M0CRPC.
(i)
Second-generation antiandrogens are considered overall safe, provided that treatment is prescribed according to current indications
(ii)
Signs of cognitive decline should be proactively watched out for during treatment with second-generation antiandrogens
(iii)
The inclusion of specific questionnaires for monitoring cognitive function in M0CRPC patients treated with second-generation antiandrogens may be useful to enhance the safety of these therapies