Relevance of Interleukins 6 and 8 Single Nucleotide Polymorphisms in Prostate Cancer: A Multicenter Study

Table 6

Relation between PSA ratio with IL-6 rs1800795 and IL-8 rs2227306 in each patient group.

		N	Min.–Max.	PSA ratio %; Mean ± SD	Median	H
Cancer group	IL-6 rs1800795
	CC	8	28.8–57.5	36.5 ± 8.8	35	2.089	0.352
	CG	14	27.2–46.9	35.1 ± 6.9	31.7
	GG	18	29.1–56.6	38.7 ± 7.3	37.6
	IL-8 rs2227306
	CC	12	27.3–47.4	35.5 ± 7.3	33.6	1.262	0.532
	CT	17	29.1–57.5	37.6 ± 8.4	36
	TT	11	27.2–46.9	37.6 ± 6.3	40
	Haplotypes of IL-6 rs1800795 and IL-8 rs2227306
	CC	17	27.3–57.5	35.1 ± 7.7	32.5	2.873	0.412
	CT	13	27.2–57.5	36.8 ± 8	35
	GC	24	27.3–56.6	37.2 ± 7.8	35.5
	GT	26	27.2–56.6	38.1 ± 6.8	40
BPH group	IL-6 rs1800795
	CC	9	15.8–24	18.2 ± 2.7	17.2	0.578	0.749
	CG	25	10.5–22.4	17.6 ± 3.5	17.2
	GG	6	10.5–21	16.4 ± 4.2	17.7
	IL-8 rs2227306
	CC	3	10.5–16.5	14.3 ± 3.3	16	2.726	0.256
	CT	24	10.5–24	17.7 ± 3.5	17.2
	TT	13	12.1–22.4	18 ± 3.2	19.2
	Haplotypes of IL-6 rs1800795 and IL-8 rs2227306
	CC	26	10.5–24	17.6 ± 3.4	17.2	4.502	0.212
	CT	17	12.5–24	18.3 ± 2.9	19.2
	GC	4	10.5–16.5	13.5 ± 3.5	13.5
	GT	33	10.5–22.4	17.6 ± 3.5	18.8

H: Kruskal–Wallis test, : value for association between different categories.