Research Article

Parkin Exon Rearrangements and Sequence Variants in LRRK2 Mutations Carriers: Analysis on a Possible Modifier Effect on LRRK2 Penetrance

Table 1

Oligonucleotides used for the ASOs technique. The nucleotide change in the oligonucleotides is underlined.

Exon 311441 wild-type allele R -CCCTCCAGGCTCGCGCTTC-
1441 mutant allele C -CCCTCCAGGCTTGCGCTTC-
1441 mutant allele G -CCCTCCAGGCTGGCGCTTC-
1441 mutant allele H -CCCTCCAGGCTCACGCTTC-

Exon 412019 wild-type allele G -AAAGATTGCTGACTACGGCA-3
2019 mutant allele S -AAAGATTGCTGACTACAGCA-
2020 wild-type allele I -GCATTGCTCAGTACTGCTGT-
2020 mutant allele T -GCACTGCTCAGTACTGCTGT-