Paired-Pulse Inhibition in the Auditory Cortex in Parkinson's Disease and Its Dependence on Clinical Characteristics of the Patients
Figure 1
Cortical auditory evoked potentials at paired-pulse stimulation with interstimulus intervals 700 and 900 ms in the age-matched healthy subject and in the patient with Parkinson’s disease (PD). N1 (I), P2 (I)—the components of evoked potentials on the first conditional and N1 (II), P2 (II)—on the second test stimuli. In the PD patient, the N1-P2 complexes appearing on second stimuli have greater amplitudes, hence the postexcitatory inhibition is reduced compared to control subject. Vertical solid bars correspond to the onset of auditory signals. Numerals in % represent value of paired-pulse inhibition calculated using the following formula: ()/A1100 where A1 and A2 are amplitudes of the N1 (I)/ P2 (I) and N1 (II)/ P2 (II) components, respectively.
