Medication Responsiveness of Motor Symptoms in a Population-Based Study of Parkinson Disease

Table 3

Total Motor UPDRS ON and OFF medication by medication status (𝑛=193).

	Medication status*
	Levodopa only (𝑛=67) mean (SD)	Levodopa and any other medication (𝑛=108) mean (SD)	Dopamine agonists without levodopa (𝑛=17) mean (SD)	ANOVA 𝑃 value
Total Motor UPDRS ON medication	17.3 (11.9)^a	17.3 (10.4)^a	14.8 (8.1)^a	0.65
Total Motor UPDRS OFF medication	24.6 (12.1)^a	25.8 (12.0)^a	20.9 (7.5)^b	0.26
Difference between ON and OFF	7.3 (4.6)^a	8.5 (5.4)^a	6.1 (4.6)^a	0.11
Hoehn and Yahr–OFF medication	𝑁 (%)	𝑁 (%)	𝑁 (%)	Chi-square 𝑃-value
1	4 (5.9)	4 (3.7)	2 (11.7)	0.76
1.5	3 (4.5)	8 (4.7)	1 (5.9)
2	23 (34.3)	35 (32.4)	6 (32.3)
2.5	22 (32.8)	27 (25.0)	5 (29.4)
3	10 (14.9)	20 (18.5)	3 (17.7)
4	2 (3.0)	10 (9.3)	0 (0.0)
5	3 (4.5)	4 (3.7)	0 (0.0)