Clinical Study
Neuropsychiatric Symptoms in Parkinson's Disease with Mild Cognitive Impairment and Dementia
Table 6
Correlations between behavioural scores and key demographic, disease, and cognitive variables.
|
| Self-rated
| Informant-rated
| | (participants without dementia; ) | (all participants; ) | | Apathy Scale
| NPIviii-apathy | NPI-psychosis
| | (hallucinations or delusions) |
| Demographic and disease variables | ; value
|
| Age | | | | LEDDii | | | | LEDD-DAiii |
−0.38; <0.001 | | | Age of onset | | | | Duration of illness | | | | Hoehn-Yahr | | | | UPDRSi motor | | | | UPDRS complication | | | | MMSEiv |
−0.41; <0.001 | | |
| |
Self-rated scales in the participants without dementia | | Apathy Scale
| HADSvi-depression | HADS -anxiety
|
| Cognitive measures | ; value |
| Trails B-Trails A (reaction time in seconds) | | | | Serial 7’s | | | | Digit -back | | | | cWCSTx | | | | FASix total | | | | 5-min recall of three words | | | | Intersecting pentagons | | | |
|
|
iUnified Parkinson’s Disease Rating Scale; xcomputerised version of the Wisconsin Card Sorting Test;
iitotal daily dopaminergic load based on levodopa equivalents or “levodopa equivalent daily dose”; iiilevodopa equivalent daily dose-dopamine agonist only; ivMini-Mental State Exam; viHADS: Hospital Anxiety and Depression Rating Scale; viiiNeuropsychiatric Inventory; ixverbal fluency FAS test.
|