Individual Characteristics Task and Environmental Characteristics Results Study (PD sample) Age (yrs) Disease severity Cog. Walking task & environment Concurrent task Instruct. Walking DTC Concurrent task DTC
Bond and Morris, 2000 [40 ] (
) 65 (10) Webster score: 13 (5) STMS: 30 (4) Walk 10 m (comfortable pace) Motor: (1) carry tray; (2) carry tray with empty glasses No prioritization Speed: (1) −2%; (2) −11% Stride length: (1) +1%; (2) −1% DLS: (1) −2%; (2) −2% — Brown et al., 2009 [41 ] (
) 67 (7) UPDRS: 28 (2) H&Y: 2.3 (0.3) MMSE: ≥26 Walk 10 m (self- selected pace, unobstructed walkway) Cognitive: serial-3 subtraction (data presented for no music trials) None provided Speed: −20% Stride length: −6% DLS: −12% — Camicioli et al., 1998 [53 ] (
) 67 (9) Off-med On-med UPDRS: 15 (4) UPDRS: 12 (6) MMSE: 27 (1) Walk 4.6 m, turn 180°, walk 4.6 m (self-selected pace) Cognitive: verbal fluency (recite male names) Not specified Steps: −40% Time: −50% Steps: −16% Time: −31% — — Campbell et al., 2003 [54 ] (
) 74 (7) H&Y: 2.8 (0.8) — Timed Up and Go (3 m; comfortable pace) Cognitive: (1) repeat phrase; (2) repeat days of the week backwards Not specified Steps: (1) +1%; (2) −13% Time: (1) −1%; (2) −31% — Galletly and Brauer, 2005 [42 ] (
) 65 (10) UPDRS: 14 (6) MMSE: 28 (3) Walk 10 m (comfortable pace) Motor: (1) button press Cognitive: (2) serial-3 subtraction; (3) verbal fluency “Concentrate on both tasks” Speed: (1) −7%; (2) −21%; (3) −21% Stride length: (1) −4%; (2) −16%; (3) −16% Motor: (1) +16% Cognitive: (2) +31%; (3) +73% Hackney and Earhart, 2009 [55 ] (
) 65 (10) UPDRS: 28 (9) — Walk 5 m (comfortable pace) both forward and backward Cognitive: mental arithmetic (serial-3, 4, and 6 subtraction) Not specified
*Speed: −33% *Stride length: −14% — Hausdorff et al., 2003 [49 ] (
) Range: 52–82 UPDRS: 14 H&Y: 3.1 MMSE: 27 Walk 20 m (normal pace; level ground) Cognitive: serial-7 subtraction “Walk while performing subtractions” Stride time: −10% Stride time variability: −154% —
LaPointe et al., 2010 [56 ] (
) 67 H&Y: 2.4 (7) DRS-2: 136 (7) Walk 4.3 m Cognitive: (1) count by 1’s; (2) serial-3 subtraction; (3) recite alpha-numeric sequence Not specified
**Speed: (1) −2%; (2) −12%; (3) −19% **Stride length: (1) −1%; (2) −6%; (3) −10% DLS: (1) −4%; (2) −9%; (3) −10% — Lord et al., 2010 [43 ] (
) 71 (7) Off-med
UPDRS: 39 (15) MMSE: 27 (3) Stand from a chair, walk 5–11 m (preferred speed; examined in home & distance varied by home) Motor: (1) carry tray with 2 beakers of water Cognitive: (2) count auditory tones (3) Motor + Cognitive “Concentrate equally on walking and task(s)” Speed: (1) −24%; (2) −14%; (3) −32% — Lord et al., 2011 [57 ] (
) 69 (7) Off-med On-med
UPDRS: 35 (9) UPDRS: 23 (9) MMSE: 28 (2) Walk 6 m, turn 180°, walk 6 m (examined in home) Motor: carrying a tray with 2 cups of water “Concentrate on task as a whole” Speed: −13% Stride time Variability: −8% Speed: −11% Stride time Variability: −21% — O’Shea et al., 2002 [44 ] (
) 68 (7) Modified Webster Scale:12 (6) STMS: 30 (3) Walk 10 m (preferred pace) Motor: (1) coin transfer Cognitive: (2) serial-3 subtraction Not specified Speed: (1) −18%; (2) −19% Stride length: (1) −14%; (2) −12% DLS: (1) −3%; (2) −6% Motor: (1) −17.4% Cognitive: (2) −5% Plotnik et al., 2009 [48 ] (
) 72 (7) UPDRS: 20 (8) MMSE: 28 (1) Walk 2 min in a level, 25 m corridor (comfortable pace) Cognitive: serial-7 subtraction No prioritization Phase coordination index: −47% — Plotnik et al., 2011 [45 ] (
) 66 (7) UPDRS: 35 (10) H&Y: 2.1 (0.6) MMSE: 29 (1) Walk ~80 m in a level, ~20 m corridor (comfortable pace) Cognitive: (1) serial-3 subtraction; (2) serial-7 subtraction Not specified Speed: (1) −17%; (2) −23% Stride length: (1) −11%; (2) −15% Stride time variability: (1) −39%; (2) −51% — Rochester et al., 2004 [46 ](
) 65 (8) H&Y: 2.7 (0.7) MMSE: 27 (2) Stand from a chair, walk 6.6 (1.5) m, return (preferred speed, examined in home & distance varied by home) Motor: (1) carrying tray with 2 cups of water; Cognitive: (2) autobiographical memory task;(3) Motor + Cognitive Not specified Speed: (1) −9%; (2) −21%; (3) −23% Step length: (1) −9%; (2) −16%; (3) −21% — Rochester et al., 2008 [58 ] (
) 67 (8) UPDRS: 33 (11) MMSE: 28 (2) Walk 6 m, turn 180°, walk 6 m (preferred pace) Motor: carrying a tray with 2 cups of water “Concentrate equally on all tasks” Speed: −13% — Spildooren et al., 2010 [59 ] Freezers (
) 69 (7) Off-med UPDRS: 38 (14) H&Y: 2.5 (0.5) MMSE: 28 (1)
Walk 5 m: (1) straight; (2) turn 180°; (3) turn 360°
Cognitive: color identification (auditory attentional task)
No prioritization Steps: (1) −25%; (2) −16%; (3) −13% Time: (1) −23%; (2) −13%; (3) −10% — Non-freezers (
) 67 (7) Off-med UPDRS: 34 (10) H&Y: 2.4 (0.3) MMSE: 29 (1) Steps: (1) −7%; (2) +1%; (3) −2% Time: (1) −9%; (2) −1%; (3) −3% — Yogev et al., 2005 [50 ] (
) 71 (8) UPDRS: 18 (8) H&Y: 2.3 (0.4) MMSE: 28 (2) Walk 2 min in a level, 25 m corridor (comfortable pace) Cognitive: (1) listen to a tape & answer questions; (2) above task + phoneme monitoring; (3) serial-7 subtraction No prioritization Speed: (1) −10%; (2) −13%; (3) −19%Stride time variability: (1) −1%; (2) −6%; (3) −27% Cognitive: (1) −42% Yogev et al., 2007 [47 ] (
) 72 (7) UPDRS: 20 (8) H&Y: range 2-3 MMSE: 28 (1) Walk 2 min in a level, 25 m corridor(comfortable pace) Cognitive: serial-7 subtraction No prioritization Gait asymmetry: −43% —