Table 3: Multivariate linear regression model for the effect of EOPD on health-related quality of life (QoL) score and its interactions with other determinant factors.

Scales/VariablesCoefficientsWald Chi295% CI for value
SEMLower boundUpper bound

EOPD−3.715.70.1−34.327.10.814
Female sex2.91.73.0−0.46.20.082
Education level
 Illiterate0 (ref.)
 Primary and/or Secondary−3.62.81.6−9.12.00.208
 High School/Diploma−2.82.91.0−8.42.80.323
 College and/or University−3.82.81.8−9.31.70.176
Comorbidity index0.20.80.1−1.41.80.812
Hoehn & Yahr stage0.80.90.8−1.02.70.384
Nutritional status (MNA score)−0.50.41.8−1.30.20.184
 Interaction with EOPD 0.10.50.0−0.91.20.829
Anxiety (HADS score)0.60.28.90.21.0
 Interaction with EOPD0.20.40.2−0.60.90.695
Depression (HADS score)1.50.326.70.92.0<0.00
 Interaction with EOPD−0.50.50.9−1.50.50.344
Fatigue (FSS score)0.10.13.3−0.00.20.071
 Interaction with EOPD0.00.10.0−0.20.20.846

Statistically significant factor at the significance level of 0.05 (2-tailed).
(Multivariate adjustment has been performed considering sex, education level, comorbidity index, and Hoehn and Yahr stage as potential confounders).