Table 3: Multivariate linear regression model for the effect of EOPD on health-related quality of life (QoL) score and its interactions with other determinant factors.

Scales/VariablesCoefficientsWald Chi295% CI for value
SEMLower boundUpper bound

Female sex2.91.73.0−
Education level
 Illiterate0 (ref.)
 Primary and/or Secondary−−
 High School/Diploma−−
 College and/or University−−
Comorbidity index0.20.80.1−
Hoehn & Yahr stage0.80.90.8−
Nutritional status (MNA score)−−
 Interaction with EOPD−
Anxiety (HADS score)
 Interaction with EOPD0.20.40.2−
Depression (HADS score)1.50.326.70.92.0<0.00
 Interaction with EOPD−−
Fatigue (FSS score)−
 Interaction with EOPD0.00.10.0−

Statistically significant factor at the significance level of 0.05 (2-tailed).
(Multivariate adjustment has been performed considering sex, education level, comorbidity index, and Hoehn and Yahr stage as potential confounders).